AI Article Synopsis
- The study examined how extract of Ginkgo biloba (EGb) affects blood flow in the brains of rats after a subarachnoid hemorrhage (SAH) incident.
- SAH led to higher intracranial pressure and lower cranial perfusion pressure in all groups, but rats treated with EGb experienced smaller increases in intracranial pressure compared to those that received a vehicle treatment.
- The findings suggest that EGb helps reduce the negative effects on blood flow and pressure in the brain following SAH.
Article Abstract
The purpose of this study was to investigate in effect of extract of Ginkgo biloba (EGb) on cerebral blood perfusion in a subarachnoid haemorrhage (SAH) rat model. SAH lead to an increase in intracranial pressure and decrease in cranial perfusion pressure and regional cerebral blood flow in all groups. However, the intracranial pressure increases in EGb groups were less than that of the vehicle group (p < .01), whereas the reduction in cranial perfusion pressure and regional cerebral blood flow in the EGb group was less than that of the vehicle and SAH groups (p < .01). It was concluded that EGb attenuates the increase in intracranial pressure and reduction in cerebral blood perfusion after SAH.
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| http://dx.doi.org/10.1080/00207450600773871 | DOI Listing |
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