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Effects of cold-pressed wheat germ oil and Bacillus subtilis on growth performance, digestibility, immune status, intestinal microbial enumeration, and gene expression of broilers under heat stress.
Poult Sci
December 2024
Department of Biochemistry, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
This study evaluated the effect of wheat germ oil (WGO), Bacillus subtilis, and their combination on growth performance, immune response, nutrient digestibility, intestinal microbial, oxidative status, and gene expression in heat-stressed broilers. Four hundred one-day-old male Ross 308 broilers were distributed into five pens (20 birds/pen) in four experimental groups: a control (CON) without additives, WGO group fed diet with WGO at 200 mg.kg, BS group fed diet with B.
View Article and Find Full Text PDFAlterations in LDL and HDL after an ischemic stroke associated with carotid atherosclerosis are reversed after 1 year.
J Lipid Res
December 2024
Cardiovascular Biochemistry Group, Institut de Recerca Sant Pau, (IR Sant Pau), Barcelona, Spain; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Spain. Electronic address:
Approximately 20% of ischemic strokes are attributed to the presence of atherosclerosis. Lipoproteins play a crucial role in the development of atherosclerosis, with LDL promoting atherogenesis and HDL inhibiting it. Therefore, both their concentrations and their biological properties are decisive factors in atherosclerotic processes.
View Article and Find Full Text PDFAssociation of nitric oxide levels and lipid profile with endothelial dysfunction in type 2 diabetic patients.
J Res Med Sci
October 2024
Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.
Article Synopsis
- Evidence-based screening is essential for detecting myocardial ischemia in high-risk diabetics, particularly by analyzing nitric oxide levels, lipid profiles, and atherogenic indices in those with coronary artery disease (CAD).
- A study involved 50 diabetics with CAD, 30 without CAD, and 23 healthy individuals, measuring various biochemical parameters and plasma nitric oxide through the Griess reaction.
- Results indicated that diabetics with CAD had elevated levels of nitric oxide and triglycerides, whereas their cholesterol levels were lower, and there was a significant positive correlation between nitric oxide and glycated hemoglobin, highlighting the link between chronic hyperglycemia and potential vascular complications in diabetes.
Article Synopsis
- The study focuses on understanding how different types of exercise and metformin impact vascular health in diabetic rats, particularly looking at oxidative stress and inflammation.
- The research involved inducing diabetes in rats and subjecting them to various treatments, revealing that all treatments improved crucial biochemical markers related to diabetes.
- Notably, combining exercise with metformin showed greater benefits, especially with interval training, suggesting a dual approach could enhance therapy for diabetes-related cardiovascular issues.
Therapeutic Efficacy of Salvia chudaei Ethanol Extract in Hyperlipidemia, Hyperglycemia, and Oxidative Stress in Triton X-100-Induced Wistar Rats.
Chem Biodivers
December 2024
Brown University, Pathology and Laboratory Medicine, USA, USA, UNITED STATES OF AMERICA.
The study explored the efficacy of Salvia chudaei ethanolic extract in managing hyperlipidemia, hyperglycemia, and oxidative stress induced by Triton X-100 in Wistar rats. Twenty-four rats were divided into four groups: Control, Salvia chudaei-treated, Triton-induced hyperlipidemic, and a combination of Triton + Salvia chudaei treatment. Triton X-100 raised serum levels of total cholesterol, triacylglycerol, and LDL while lowering HDL cholesterol, leading to oxidative stress marked by increased MDA and reduced antioxidant activity in liver and kidney tissues.
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