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Scleroderma-Like Lupus Panniculitis: A Case Report and Literature Review.
Clin Cosmet Investig Dermatol
April 2023
Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sclerodermic or scleroderma-like lupus erythematosus panniculitis (SLEP) shares both clinical and histopathological features between lupus panniculitis and localized scleroderma. It is exceedingly rare. We herein report a case of SLEP manifested with a solitary, firm-to-hard, erythematous plaque in an Asian woman.
View Article and Find Full Text PDFFrom Morphea to Dermatofibrosarcoma Protuberans.
Acta Dermatovenerol Croat
September 2022
Marija Delaš Aždajić, MD, PhD, Department of Dermatology and Venereology Sestre milosrdnice University Hospital Center, Vinogradska cesta 29 , 10 000 Zagreb , Croatia ;
Article Synopsis
- - Morphea profunda (MP) is a chronic autoimmune disease that leads to restricted skin movement and discomfort, while dermatofibrosarcoma protuberans (DFSP) is a rare, slowly growing tumor that can invade deeper tissues and has a tendency to recur locally but rarely spreads to other parts of the body.
- - A 39-year-old female patient had a brownish lesion diagnosed as MP at 20, which later developed into palpable nodules, leading to further evaluation and a new diagnosis of DFSP after deep biopsy and immunohistochemical analysis.
- - The patient underwent complete surgical removal of the DFSP tumor, followed by additional excision due to inadequate initial margins, and has shown no signs of
AESOP syndrome: a potential life-saving and early clue to the diagnosis of POEMS syndrome.
Clin Dermatol
November 2021
Faculté de Médecine, Université de Strasbourg et Clinique Dermatologique, Hôpitaux Universitaires de Strasbourg, Strasbourg, France. Electronic address:
Adenopathy and an extensive skin patch overlying a plasmacytoma (AESOP) syndrome, first described 16 years ago, is characterized by a slowly expanding red or brown patch (classic variant) or plaque (morphea-like variant) overlying a solitary plasmacytoma of the bone. Early recognition can be life-saving, as it is an early presentation of polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome, which may be fatal. There are two forms: the classic variant, which presents as a smooth, shiny macule with abnormal visibility of skin vessels, and the morphea-like variant, which presents as a plaque where the skin is folded, giving a "peau d'orange" appearance.
View Article and Find Full Text PDFPediatric-onset solitary morphea profunda.
Int J Dermatol
March 2021
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
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