Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ja0710508 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recombinant human FOXJ1 protein binds DNA, forms higher-order oligomers, has gel-shifting domains and contains intrinsically disordered regions.
Protein Expr Purif
March 2025
School of Biological Sciences, UM-DAE Center for Excellence in Basic Sciences, University of Mumbai, Kalina Campus, Santacruz (E), Mumbai, 400098, India. Electronic address:
Forkhead box protein J1 (FOXJ1) is the key transcriptional regulator during the conversion of mammalian primary cilium with a 9 + 0 architecture to the motile (9 + 2) one. The nucleotide sequences of the full-length and DNA-binding domain (DBD) of the open reading frame (ORF) were isolated and expressed into E. coli as 6xHis-tagged proteins.
View Article and Find Full Text PDFCysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells.
Arch Toxicol
November 2023
Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentska 95, 532 10, Pardubice, Czech Republic.
Acetaminophen (APAP) belong among the most used analgesics and antipyretics. It is structurally derived from p-aminophenol (PAP), a potent inducer of kidney toxicity. Both compounds can be metabolized to oxidation products and conjugated with glutathione.
View Article and Find Full Text PDFA new insight into the hepatoprotective effect of sildenafil: The role of HS.
Naunyn Schmiedebergs Arch Pharmacol
November 2023
Department of Pharmacology, Faculty of Pharmacy, Ege University, 35100, Bornova, Izmir, Turkey.
High-calorie diet, alcohol, and multiple drug use increase reactive oxygen species (ROS) and cause liver damage. ROS are crucial in the initiation/progression of liver diseases. Antioxidants have beneficial effects but produce clinically complex results.
View Article and Find Full Text PDFStimulation of mitochondrial hydrogen sulfide and glutathione production improves the Frank-Starling response of the rat heart via a nitric oxide-dependent pathway.
Can J Physiol Pharmacol
January 2022
Department of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
The Frank-Starling response of the heart is known to be mediated by nitric oxide (NO) signaling, which is regulated by reduced glutathione (GSH) and hydrogen sulfide (HS). We hypothesized that stimulation of endogenous HS or GSH synthesis would improve the Frank-Starling response. Wistar male rats were injected with propargylglycine (PAG; 11.
View Article and Find Full Text PDFCysteine-induced alterations in physicochemical parameters of oat (Avena sativa L. var. Scott and F-411) under drought stress.
Biol Futur
January 2019
Department of Botany, Government College University, Faisalabad, Pakistan.
Introduction: Drought is one of the major abiotic stresses that drastically reduces crop yield throughout the world. Being precursor of glutathione biosynthesis and involvement in other metabolic processes, cysteine (Cys) has been shown to alter growth and development in plants. In this context, we investigated Cys-induced physicochemical alterations in oat (Avena sativa L.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!