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Clinical course and management of pediatric gastroduodenal perforation beyond neonatal period.
Pediatr Neonatol
December 2024
Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Japan. Electronic address:
Background: The treatments and outcomes of pediatric gastroduodenal perforations have rarely been described.
Methods: We retrospectively identified 515 patients aged 28 days to 17 years who were hospitalized for gastroduodenal perforation between July 2010 and March 2021 using a nationwide inpatient database. We compared characteristics, treatments, and outcomes for pediatric gastroduodenal perforation between children aged <7 years (n = 38) and ≥7 years (n = 477).
Education, intelligence, and 20 gastrointestinal disorders: A Mendelian randomization study.
Medicine (Baltimore)
December 2024
Hepatobiliary Surgery, Chaohu Hospital of Anhui Medical University, Hefei, China.
Previous observational studies have suggested that higher levels of education attainment and intelligence (IQ) are associated with better health outcomes in humans. However, the causal link between education attainment and IQ and their association with health outcomes remains unclear. This study aims to investigate the distinct impacts of intelligence and educational attainment on gastrointestinal symptoms.
View Article and Find Full Text PDFIs distal pancreatectomy the optimal surgical procedure for pancreatic neck cancer?
Surgery
February 2025
Department of Surgery, Kurashiki Central Hospital, Kurashiki, Japan.
Article Synopsis
- The study investigates the best surgical options for pancreatic neck cancer, comparing pancreaticoduodenectomy (PD) and distal pancreatectomy (DP) among 462 patients treated from 2012 to 2022.
- It identifies lymph node station #11p as having the highest rate of metastasis (28.6%) and shows that PD with #11p dissection offers better survival outcomes compared to DP, despite no significant survival differences overall between the two procedures.
- Researchers found that larger tumor size (≥2 cm) correlates with worse prognosis, highlighting the importance of lymph node dissection in surgical planning for pancreatic neck cancer.
A ligamentum teres hepatis and falciform ligament 'belt and braces' approach in laparoscopic pancreaticoduodenectomy using a modified Blumgart anastomosis to minimize severe pancreatic fistula and post-operative complications.
Surg Oncol
December 2024
Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China; Shanghai Pancreatic Cancer Institute, Shanghai, 200032, China; Pancreatic Cancer Institute, Fudan University, Shanghai, 200032, China. Electronic address:
Article Synopsis
- A study was conducted to evaluate how using the ligamentum teres hepatis and falciform ligament, which wraps around the gastroduodenal artery (GDA), impacts complications after laparoscopic pancreaticoduodenectomy (LPD).
- Patients were divided into two groups: one with the ligamentous flap wrapping the GDA stump (Group A) and another that utilized the flap for both GDA wrapping and reinforcing the posterior wall (Group B).
- Group B showed fewer complications like clinically relevant post-operative pancreatic fistulas, shorter hospital stays, and less need for abdominal drainage, indicating that this technique enhances the safety and outcomes of LPD.*
Sedentary and 21 gastrointestinal disorders: A Mendelian randomization study.
Medicine (Baltimore)
September 2024
Department of Hepatobiliary Surgery, Chaohu Hospital of Anhui Medical University, Hefei, China.
Sedentary behavior (SB) has been linked in the past by observational studies to gastrointestinal illnesses, although the exact cause of the link is still unknown. To deal with this problem, we carried out a Mendelian randomization (MR) study to thoroughly examine the connection between SB and common gastrointestinal illnesses. We selected instrumental variables representing the SB from the UK Biobank study, including watching television viewing, playing computer, and driving.
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