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Nonoperative management for disseminated spinal blastomycosis with extensive lytic destruction in a 35-year-old male: illustrative case.
J Neurosurg Case Lessons
December 2024
Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi.
Article Synopsis
- A 35-year-old male presented with back pain and masses on his arms, having a previous sacral lesion suspected to be a fungal infection that was never fully investigated.
- CT and MRI showed destructive bone lesions indicating a possible disseminated infection, and biopsies confirmed the presence of Blastomyces dermatitidis.
- Despite initial concerns about his condition, the patient had no neurological deficits and showed improvement with medical treatment, highlighting the importance of clinical evaluation in making surgical decisions for spinal fungal infections.
Blastomycosis.
Infect Dis Clin North Am
December 2024
Division of Infectious Diseases, Department of Internal Medicine, F4005 University Hospital South, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:
Blastomycosis is caused primarily by Blastomyces dermatitidis. The fungus is a mold in the environment, causing infection when conidia are dispersed and inhaled. In the lungs, the organism transforms into the yeast phase.
View Article and Find Full Text PDFAn Unusual, Symmetric Rash on Both Forearms in a 94-Year-Old Patient A Clinicopathological Challenge and Diagnostic Pitfall.
J Cutan Pathol
February 2025
Department of Dermatology, University Hospital Basel, Basel, Switzerland.
Article Synopsis
- Trichophyton rubrum (T. rubrum) typically causes minor skin infections, mostly affecting healthy individuals, but can lead to serious infections in immunocompromised patients.
- A unique case involved a 94-year-old man with an invasive T. rubrum infection on both forearms, which resembled cutaneous blastomycosis.
- Diagnosis is complicated as T. rubrum can present with large spore-like structures that mimic Blastomyces dermatitidis, underscoring the necessity for culture or PCR testing for accurate identification.
Overview of Fungi Classified as Risk Group 3 by the Japanese Society for Medical Mycology.
Med Mycol J
December 2024
Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences.
Article Synopsis
- Fungi are classified into four Risk Groups based on their potential to harm humans, with Risk Group 3 indicating significant dangers, including fatalities.
- This review highlights dangerous fungi like Blastomyces dermatitidis and Cladophialophora bantiana, which are known for severe health impacts and high mortality rates due to laboratory-acquired infections.
- Strict biosafety measures are essential in labs handling these fungi due to their associated risks and documented cases of infections and deaths.
Article Synopsis
- - A study was done on a cluster of blastomycosis cases affecting both humans and dogs in a Wisconsin neighborhood.
- - Researchers interviewed residents and gathered blood samples to test for Blastomyces antibodies using enzyme immunoassay techniques.
- - While no clear cause was identified, possible exposure sources include the nearby riverbank, trails, yards, or dust from construction activities.
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