Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1. | LitMetric

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Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1. | LitMetric

Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1.

James C Barrow Kenneth E Rittle Phung L Ngo Harold G Selnick Samuel L Graham Steven M Pitzenberger Georgia B McGaughey Dennis Colussi Ming-Tain Lai Qian Huang Katherine Tugusheva Amy S Espeseth Adam J Simon Sanjeev K Munshi Joseph P Vacca

ChemMedChem

Department of Medicinal Chemistry, Merck Research Laboratories, P.O Box 4, WP14-1, West Point, PA 19486, USA.

Published: July 2007

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http://dx.doi.org/10.1002/cmdc.200700038 DOI Listing

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