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LEANBH study: Device satisfaction study for the use of a novel connected home blood pressure system in pregnancy; a prospective cohort study.
Pregnancy Hypertens
January 2025
INFANT Research Centre, Cork, Ireland; Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland. Electronic address:
Objectives: To investigate patients' perspectives on using the LEANBH app (home Blood Pressure BP monitoring system) and the Microlife Watch BP home monitor in a tertiary maternity hospital setting during the COVID-19 pandemic.
Study Design: 134 Participants were asked to complete an anonymous usability questionnaire on their experience of LEANBH and the Microlife Watch. The questionnaire consisted of 5 background demographics, 9 items from the system usability scale (SUS), 14 items on the usability of the LEANBH app, and 6 on the acceptability of Microlife.
Determining safety, usability, acceptability and potential for clinical use of an innovative walking frame design with in- and community patients.
Disabil Rehabil Assist Technol
January 2025
Centre for Human Movement and Rehabilitation, School of Health & Society, University of Salford, Salford, Greater Manchester, UK.
Purpose: Falls cost the NHS over £2 billion a year, with incidence increasing rapidly with age. Design of indoor walking frames remains limited, often needing to be lifted and not supporting sit-to-stand and turning manoeuvres, which can lead to falling. This study explored aspects of safety and satisfaction and potential for clinical use of a novel prototype walking frame.
View Article and Find Full Text PDFLipid-Lowering Efficiency and Safety of Alirocumab 300 mg Using a 2-mL Autoinjector Device in Real-World Practice: The MARS Study.
Drugs Real World Outcomes
January 2025
Department of Cardiology, Angiology and Intensive Care Medicine, German Heart Center of the Charité, Berlin, Germany.
Background: Alirocumab is a fully human monoclonal antibody to proprotein convertase subtilisin kexin type 9 used for the reduction of low-density lipoprotein cholesterol (LDL-C) in high-risk patients not reaching their LDL-C target. Recently, a 2-mL prefilled autoinjector has been developed to support the monthly 300-mg dosing regimen with a single-injection administration.
Methods And Objectives: Monthly application of 300 mg AlirRocumab (Praluent) using the 2-mL SYDNEY Device (MARS) is a non-interventional, open, prospective, multi-center cohort study conducted in Germany between 2021 and 2023 with an observational period of 12 weeks.
Background: Mental health remains among the top 10 leading causes of disease burden globally, and there is a significant treatment gap due to limited resources, stigma, limited accessibility, and low perceived need for treatment. Problem Management Plus, a World Health Organization-endorsed brief psychological intervention for mental health disorders, has been shown to be effective and cost-effective in various countries globally but faces implementation challenges, such as quality control in training, supervision, and delivery. While digital technologies to foster mental health care have the potential to close treatment gaps and address the issues of quality control, their development requires context-specific, interdisciplinary, and participatory approaches to enhance impact and acceptance.
View Article and Find Full Text PDFTesting an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study.
JMIR Form Res
January 2025
Centre for Patient Reported Outcomes Research, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Background: Traumatic brain injury (TBI) is a significant public health issue and a leading cause of death and disability globally. Advances in clinical care have improved survival rates, leading to a growing population living with long-term effects of TBI, which can impact physical, cognitive, and emotional health. These effects often require continuous management and individualized care.
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