Antiproliferative effects of some N-benzylideneanilines.

Cell Biochem Funct

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.

Published: September 2009

A series of Schiff bases including N-benzylideneaniline (NBA) nuclei were prepared. The chemical products obtained were characterized by mass spectometry (APCI), 1H NMR, and IR spectroscopy in order to seek their cytotoxic and proliferation effects on human small lung (A549) and cervical (HeLa) cancer cell lines with biochemical assays. All of the synthesized compounds showed antiproliferative effects to different extents.

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http://dx.doi.org/10.1002/cbf.1406DOI Listing

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