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Primary signet-ring cell carcinoma of the prostate involving the pelvis: a case report.
Front Oncol
December 2024
Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Background: Signet-ring cell carcinoma (SRCC) originates from undifferentiated stem cells in the neck of glands within the lamina propria of the mucosa. Primarily affecting the stomach, SRCC can also involve the breast, pancreas, gallbladder, colon, and bladder, although these cases are rare. SRCC of the prostate is extremely rare, and diagnosing it pelvic puncture is particularly challenging.
View Article and Find Full Text PDFMMP-3 and TIMP-1 as prognostic biomarkers in VZV-induced retinal necrosis.
Front Cell Infect Microbiol
December 2024
Department of Laboratory Medicine, Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Objective: Acute retinal necrosis (ARN) caused by varicella-zoster virus (VZV) is associated with changes in specific proteins in the eye's fluid, particularly matrix metalloproteinase-3 (MMP-3), an enzyme that breaks down tissue structures, and tissue inhibitor of metalloproteinase-1 (TIMP-1), which regulates MMP activity. This study aims to investigate how these proteins correlate with the progression of ARN.
Methods: We analyzed aqueous humor samples from 33 patients with ARN and 23 control patients with virus-negative uveitis.
Use of conjoint analysis to weight biosecurity practices on pasture-based dairy farms to develop a novel audit tool-BioscoreDairy.
Front Vet Sci
December 2024
Moorepark, Teagasc, Animal and Grassland Research and Innovation Centre, Fermoy, Co. Cork, Ireland.
Risk assessments are important tools to identify deficits in biosecurity management practices. A major strength of some existing tools is that they facilitate cross-country comparisons. However, a weakness is their failure to account for unique intra-national farming enterprise structures such as, for example, pasture-based dairying.
View Article and Find Full Text PDFLong-term trajectories of depressive symptoms by military affiliation.
SSM Popul Health
March 2025
Department of Human Development and Family Studies, Purdue University, USA.
Objectives: Using a national sample of Americans, this study estimated and compared patterns of depressive symptom trajectories stratified by military service. This study then examined associations between sociodemographic factors theorized to shape entry into military service and trajectory patterns.
Method: Data came from the National Longitudinal Study of Adolescent to Adult Health, a nationally representative study that followed participants from adolescence (1994-1995) through midlife (2016-2018).
Automatic screening for posttraumatic stress disorder in early adolescents following the Ya'an earthquake using text mining techniques.
Front Psychiatry
December 2024
Faculty of Psychology, Beijing Normal University, Beijing, China.
Background: Self-narratives about traumatic experiences and symptoms are informative for early identification of potential patients; however, their use in clinical screening is limited. This study aimed to develop an automated screening method that analyzes self-narratives of early adolescent earthquake survivors to screen for PTSD in a timely and effective manner.
Methods: An inquiry-based questionnaire consisting of a series of open-ended questions about trauma history and psychological symptoms, was designed to simulate the clinical structured interviews based on the DSM-5 diagnostic criteria, and was used to collect self-narratives from 430 survivors who experienced the Ya'an earthquake in Sichuan Province, China.
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