Objective: We evaluated beliefs about, attitudes toward, and stigma associated with epilepsy in four districts of central Laos.
Method: For this study, 83 people with epilepsy, 83 family members, and 166 matched villagers in Vientiane Province were interviewed.
Results: From patients to families to villagers, there existed a significantly increasing gradient of misbeliefs. Dubbed locally as "mad pig disease," epilepsy was viewed as having a supernatural origin by 25-42% of respondents, a life-threatening disease by 60%, a disease transmissible by consumption of pork meat by 10-21%, and a disease transmissible by contact with patients' saliva by 14.5% of patients and 44% of villagers (P<0.01). Stigma was high. People thought that they should avoid contact or sharing meals with patients (15% of patients, 62% of family members, P<0.001), and that persons with epilepsy should not get a job, get married (29 and 42%, P<0.016), or raise children (33-42%).
Conclusion: Wrong beliefs may lead to stigma and hamper access to or compliance with modern epilepsy treatment. In traditional countries, education is the cornerstone of epilepsy management.
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http://dx.doi.org/10.1016/j.yebeh.2007.02.018 | DOI Listing |
J Integr Neurosci
January 2025
Department of Brain Disease Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, 230031 Hefei, Anhui, China.
Background: White matter (WM) is a principal component of the human brain, forming the structural basis for neural transmission between cortico-cortical and subcortical structures. The impairment of WM integrity is closely associated with the aging process, manifesting as the reorganization of brain networks based on graph theoretical analysis of complex networks and increased volume of white matter hyperintensities (WMHs) in imaging studies.
Methods: This study investigated changes in the robustness of WM brain networks during aging and assessed their correlation with WMHs.
Viruses
January 2025
National Center for Water Safety (CeNSia), Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Human noroviruses (HNoVs) are a leading cause of acute gastroenteritis worldwide, with significant public health implications. In this study, wastewater-based epidemiology (WBE) was used to monitor the circulation and genetic diversity of HNoVs in Rome over an eight-year period (2017-2024). A total of 337 wastewater samples were analyzed using RT-nested PCR and next-generation sequencing (NGS) to identify genogroups GI and GII and their respective genotypes.
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January 2025
Global Health Program, Washington State University Global Health-Kenya, Nairobi 00200, Kenya.
Human outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) are more common in Middle Eastern and Asian human populations, associated with clades A and B. In Africa, where clade C is dominant in camels, human cases are minimal. We reviewed 16 studies (n = 6198) published across seven African countries between 2012 and 2024 to assess human MERS-CoV cases.
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January 2025
School of Medical, Molecular and Forensic Sciences, College of Environmental and Life Sciences, Murdoch University, 90 South Street, Perth 6150, Australia.
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January 2025
Centre for Virus Research, The Westmead Institute for Medical Research, Westmead 2145, Australia.
Anogenital inflammation is a critical risk factor for HIV acquisition. The primary preventative HIV intervention, pre-exposure prophylaxis (PrEP), is ineffective in blocking transmission in anogenital inflammation. Pre-existing sexually transmitted diseases (STIs) and anogenital microbiota dysbiosis are the leading causes of inflammation, where inflammation is extensive and often asymptomatic and undiagnosed.
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