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Seeking clinical consensus on risk assessment in anatomical infravesical obstruction of boys - A Delphi study.

J Pediatr Urol

December 2024

University of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands; Department of Pediatric Urology, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, the Netherlands.

Introduction: Infravesical obstruction (IO) is a common urological condition in young boys. Patients may present with various signs and symptoms at different ages, with severity depending to a large extent on the degree of obstruction. Consensus concerning accurate and objective modalities to diagnose IO and to differentiate between an anatomical or functional cause is still lacking.

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Background: Congenital lower urinary tract obstruction (LUTO) describes a heterogeneous group of congenital malformations. Posterior urethral valves (PUV) represent the most common entity. Familial occurrence has been described, suggestive of underlying genetic factors.

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Urethral strictures are the most common complications after surgical treatments of benign prostatic hyperplasia (BPH). Despite various preventive measures, the search for medications with antiproliferative activity and the development of surgical procedures to prevent the development of urethral strictures are still relevant. We evaluated the preventive efficacy of 5-fluorouracil against urethral strictures in patients undergoing surgery for BPH.

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