A 4 x 500 mm2 cloverleaf detector system for in vivo bone lead measurement.

Med Phys

Department of Physics, Mount Allison University, 67 York Street, Sackville, New Brunswick E4L 1E6, Canada.

Published: March 2007

A 4 x 500 mm2 "cloverleaf" low energy germanium detector array has been assembled for the purpose of in vivo bone lead measurement through x-ray fluorescence. Using 109Cd as an exciting source, results are reported from a leg phantom simulating measurement of lead in a human tibia. For high activity (4.0-4.4 GBq) and low activity (0.18-0.19 GBq) sources, measurement results are reported for both the cloverleaf system and a conventional single detector system of equivalent surface area (2000 mm2). The mean uncertainty and reproducibility of measurement were both significantly improved for the cloverleaf system with a high activity 109Cd source. When using a source activity of 4.4 GBq, measurement of the phantom resulted in an average bone lead uncertainty of 0.79 microg/g and a reproducibility of 0.84 microg/g. These results represent the highest precision yet reported from a bone lead x-ray fluorescence system.

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Source
http://dx.doi.org/10.1118/1.2436973DOI Listing

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