We address the problem of knee pathology assessment by using screw theory to describe the knee motion and by using the screw representation of the motion as an input to a machine learning classifier. The flexions of knees with different pathologies are tracked using an optical tracking system. The instantaneous screw parameters which describe the transformation of the tibia with respect to the femur in each two successive observation is represented as the instantaneous screw axis of the motion given in its Plücker line coordinates along with its corresponding pitch. The set of instantaneous screw parameters associated with a particular knee with a given pathology is then identified and clustered in R(6) to form a "signature" of the motion for the given pathology. Sawbones model and two cadaver knees with different pathologies were tracked, and the resulting screws were used to train a classifier system. The system was then tested successfully with new, never-trained-before data. The classifier demonstrated a very high success rate in identifying the knee pathology.
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http://dx.doi.org/10.1007/s11517-007-0174-1 | DOI Listing |
J Exp Orthop
January 2025
Service of Orthopaedics and Traumatology, Department of Surgery EOC Lugano Switzerland.
Purpose: Subchondral bone marrow lesions (BMLs) are present in a wide range of pathologies with different prognoses. Thus, a careful diagnosis is mandatory to address them with the proper treatment. The aim of this review was to examine BMLs aetiology and their relationship with biomechanical and biological factors, to identify BMLs and help clinicians to properly recognize and treat each of these common alterations.
View Article and Find Full Text PDFNat Aging
January 2025
Discovery Center for Musculoskeletal Recovery, Schoen Adams Research Institute at Spaulding, Boston, MA, USA.
Female individuals who are post-menopausal present with higher incidence of knee osteoarthritis (KOA) than male counterparts; however, the mechanisms underlying this disparity are unknown. The most commonly used preclinical models lack human-relevant menopausal phenotypes, which may contribute to our incomplete understanding of sex-specific differences in KOA pathogenesis. Here we chemically induced menopause in middle-aged (14-16 months) C57/BL6N female mice.
View Article and Find Full Text PDFSports Biomech
January 2025
Department of Physical Therapy, George Fox University, Newberg, OR, USA.
Achilles tendinopathy (AT) is the most common running-related pathology among masters runners. Previous evidence suggests there are no differences in submaximal running biomechanics between masters runners with and without AT. Evidence suggests lower extremity power deficits are common among ageing individuals and those with AT.
View Article and Find Full Text PDFUnlabelled: The increased rate of anterior cruciate ligament (ACL) tears has led to a greater number of revisions. Revision surgery can be performed in one or two stages. Single-stage revision ACL reconstruction (ssRACLR) may be performed when prior tunnels can be re-used or bypassed whereas a two-stage procedure is indicated when bone grafting of dilated tunnels prior to revision is necessary.
View Article and Find Full Text PDFClin Nephrol Case Stud
January 2025
Department of Medicine.
Minimal change disease (MCD) accounts for 10 - 15% of idiopathic nephrotic syndromes in adults. Chronic hepatitis C virus (HCV) infection is rarely ascribed as a cause of MCD and was previously associated with interferon-based therapy. MCD in treatment-naïve chronic HCV infection is extremely rare, with only 3 cases reported in the literature.
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