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No two traumas are alike, and neither are two presentations of PTSD.
World Psychiatry
February 2025
Department of Psychiatry, Faculty of Medicine and Health Sciences, and South African Medical Research Council/Genomics of Brain Disorders Research Unit, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Effective community engagement in one health research in Sub-Saharan Africa: a systematic review.
One Health Outlook
January 2025
Department of Psychology, Faculty of Humanities, University of Johannesburg, Auckland Park, Johannesburg, South Africa.
Background: The one health (OH) approach, linking human, animal, and environmental health, relies on effective community engagement (CE), education, stewardship, and effective regional and global partnerships. For real impact, communities should be at the centre of research agenda setting and program implementation. This review aimed at synthesizing empirical evidence on how communities are involved in one health research.
View Article and Find Full Text PDFPatterns of incident Burkitt lymphoma during the HIV epidemic among the Black African and White population in South Africa.
Br J Cancer
January 2025
Medical Microbiology and Immunology, National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.
Background: Burkitt lymphoma (BL) may be HIV-associated but data on BL trends in South Africa (SA), where HIV is highly prevalent, are scarce. We compared BL incidence trends over 36 years among Black African and White individuals.
Methods: We included histologically diagnosed BL from the National Cancer Registry in SA between 1986-2021.
and gene variants affecting clopidogrel metabolism in a South Asian population from Sri Lanka.
Pharmacogenomics
January 2025
Department of Anatomy, Genetics and Biomedical Informatics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Aims: Clopidogrel exhibits substantial variability in therapeutic response, largely contributed by genetic factors. The pharmacogenomic variants data on clopidogrel metabolism in South Asians have been sparsely studied. This study explores the impact of and gene variants on clopidogrel metabolism in Sri Lankans, revealing significant pharmacogenomic insights with broader implications for South Asians.
View Article and Find Full Text PDFRecruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial.
J Med Internet Res
January 2025
Black Dog Institute, University of New South Wales, Sydney, Australia.
Background: With increasing adoption of remote clinical trials in digital mental health, identifying cost-effective and time-efficient recruitment methodologies is crucial for the success of such trials. Evidence on whether web-based recruitment methods are more effective than traditional methods such as newspapers, media, or flyers is inconsistent. Here we present insights from our experience recruiting tertiary education students for a digital mental health artificial intelligence-driven adaptive trial-Vibe Up.
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