Although the European region is polio free since 2002, the risk of importation from endemic regions remains present and a high level of population immunity must be maintained. In Romania during the period 2002-2005, 101 FP cases, 91 AFP cases and 29 healthy contacts (living in groups with low social and sanitary status, relatively low vaccination coverage named "at risk") could have been investigated serologically. Antibody prevalences for poliovirus types 1, 2, and 3 were: 97.2%, 98% and 81.2% for FP cases; 96.7%, 94.5% and 85.7% for AFP cases, and 85.7%, 82.1% and 53% for the group of healthy children at risk. The risk of the emergence and spread of cVDPVs remains present especially in "at risk" groups with the gaps in immunity, even in countries where indigenous wild polioviruses have already been eradicated.
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IJID Reg
December 2024
University of Health Sciences, Department of Bacteriology-Virology, Libreville, Gabon.
Objectives: In Gabon, data on hepatitis B virus (HBV) infection are limited to hepatitis B surface antigen (HBsAg) detection among specific populations and rural regions. This is the first study aimed at determining the seroprevalence of HBV markers among the Gabonese population.
Methods: A retrospective study was conducted from January 2002 through December 2022.
Hum Vaccin Immunother
December 2025
Immunization Program Department, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Vaccination coverage for influenza among diabetic populations remains suboptimal. Various factors contribute to this low vaccination rate, with a prominent issue being skepticism among potential vaccine recipients regarding vaccine effectiveness. We conducted a retrospective test-negative case-control study among diabetic patients aged 60 years and older in Ningbo, Zhejiang Province, China, spanning for four influenza seasons from 2018-19 to 2021-22.
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January 2025
Department of Anaesthesia, Alex Ekwueme Federal University Teaching Hospital Abakaliki (AEFUTHA), Abakaliki, Ebonyi State, Nigeria.
Optimal (timely or cumulative age-appropriate) routine childhood immunization coverage (the receipt of every recommended vaccine dose at the recommended age and time-interval between doses) will enhance optimal protection against vaccine-preventable infectious diseases (VPDs) which have been causing significant morbidity and mortality and recurring outbreaks among children younger than five years. This study evaluated optimal routine childhood immunization coverage, and the predictors, in Ebonyi state, Nigeria. This study was a baseline cross-sectional household survey within a cluster-randomised controlled trial and was conducted from July 2 to 16, 2022 among consenting mother-child pairs, in which the children were aged 5-23 months (subdivided into 5-11 and 12-23 months), in 16 randomly selected geographical clusters where the primary health care (PHC) facilities were providing maternal and child health care services including weekly routine childhood immunization.
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January 2025
Fondazione Achille Sclavo ONLUS, Via Fiorentina, Siena, 53100, Italy.
Invasive non-Typhoidal Salmonella (iNTS) is one of the leading causes of blood stream infections in Sub-Saharan Africa, especially among children. iNTS can be difficult to diagnose, particularly in areas where malaria is endemic, and difficult to treat, partly because of the emergence of antibiotic resistance. We developed a mathematical model to evaluate the impact of a vaccine for iNTS in 49 countries of sub-Saharan Africa.
View Article and Find Full Text PDFBMJ Glob Health
January 2025
The University of Sydney School of Public Health, Sydney, New South Wales, Australia.
The Sahel region is a geographical belt in Africa that stretches from the Atlantic Ocean to the Red Sea, between the Sahara Desert in the north and the Savannah in the south. It is characterised by challenging environmental crises and conflicts. This analysis highlights the potential implications of conflict on vaccination across five Sahel countries, including Burkina Faso, Chad, Mali, Niger and Sudan, from 2019 to 2023.
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