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Substitution load revisited: a high proportion of deaths can be selective.
Genetics
January 2025
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA.
Haldane's Dilemma refers to the concern that the need for many "selective deaths" to complete a substitution (i.e. selective sweep) creates a speed limit to adaptation.
View Article and Find Full Text PDFMetaverse-Aided Rehabilitation: A Perspective Review of Successes and Pitfalls.
J Clin Med
January 2025
Physical Medicine and Rehabilitation Unit, Department of Medical and Surgical Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.
: The evolution of technology has continuously redefined the landscape of rehabilitation medicine. Researchers have long incorporated virtual reality (VR) as a promising intervention, providing immersive therapeutic environments for patients. The emergence of the metaverse has recently further expanded the potential applications of VR to augment the possibilities in rehabilitation.
View Article and Find Full Text PDFOne Earth-One Health (OE-OH): Antibacterial Effects of Plant Flavonoids in Combination with Clinical Antibiotics with Various Mechanisms.
Antibiotics (Basel)
December 2024
Laboratory of Natural Medicine and Microbiological Drug, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang 330045, China.
Antimicrobial resistance (AMR) poses a significant threat to human health, and combination therapy has proven effective in combating it. It has been reported that some plant flavonoids can enhance the antibacterial effects of antibiotics and even reverse AMR. This study systematically evaluated the synergistic effects of plant flavonoids and clinical antibiotics.
View Article and Find Full Text PDFExpanding the frontiers of electrocatalysis: advanced theoretical methods for water splitting.
Nano Converg
January 2025
School of Chemical Engineering, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Electrochemical water splitting, which encompasses the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER), offers a promising route for sustainable hydrogen production. The development of efficient and cost-effective electrocatalysts is crucial for advancing this technology, especially given the reliance on expensive transition metals, such as Pt and Ir, in traditional catalysts. This review highlights recent advances in the design and optimization of electrocatalysts, focusing on density functional theory (DFT) as a key tool for understanding and improving catalytic performance in the HER and OER.
View Article and Find Full Text PDFA scalable solar-driven photocatalytic system for separated H and O production from water.
Nat Commun
January 2025
State Key Laboratory of Crystal Materials, Institute of Crystal Materials, Shandong University, Jinan, China.
Solar-driven photocatalytic water splitting offers a sustainable pathway to produce green hydrogen, yet its practical application encounters several challenges including inefficient photocatalysts, sluggish water oxidation, severe reverse reactions and the necessity of separating produced hydrogen and oxygen gases. Herein, we design and develop a photocatalytic system composed of two separate reaction parts: a hydrogen evolution cell containing halide perovskite photocatalysts (MoSe-loaded CH(NH)PbBrI) and an oxygen evolution cell containing NiFe-layered double hydroxide modified BiVO photocatalysts. These components are bridged by a I/I redox couple to facilitate electron transfer, realizing efficient overall water splitting with a solar-to-hydrogen conversion efficiency of 2.
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