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: Granulomatosis with polyangiitis (GPA) represents a rare autoimmune disease with granulomatous inflammation, tissue necrosis, and systemic vasculitis of the small and medium blood vessels. Although the clinical elements vary, aortic involvement is exceptional and it represents a challenge that requires a rapid intervention with the potential of displaying a fulminant evolution. : We report a 64-year-old male with an 18-year history of GPA who presented atypical low back pain.

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Importance: States have implemented multiple policies likely to influence opioid prescribing; few national general population studies examine those policies' effects on per-capita opioid morphine milligram equivalents (MME) dispensed.

Objective: To examine state policies' effects on opioids per-capita MMEs dispensed at retail pharmacies.

Design: A longitudinal study of associations between MME per capita and implementation of policy interventions at different times across states.

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Advancing pain education: a cross-sectional study in the Portuguese medical schools.

BMC Med Educ

January 2025

Departamento de Biomedicina da Faculdade de Medicina, Universidade do Porto, Porto, Portugal.

Introduction: Chronic pain negatively impacts on quality of life and is often underreported and undertreated. Therefore, it is essential for medical schools to provide education in pain management for students. This study evaluated the current state of pain education in the Portuguese medical schools, focusing on integrating pain-related topics into the curriculum.

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Background Context: Clinical outcomes are directly related to patient selection and treatment indications for improved quality of life. With emphasis on quality and value, it is essential that treatment recommendations are optimized.

Purpose: The purpose of the North American Spine Society (NASS) Appropriate Use Criteria (AUC) is to determine the appropriate (ie, reasonable) multidisciplinary treatment recommendations for patients with metastatic neoplastic vertebral fractures across a spectrum of more common clinical scenarios.

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Nil by mouth in intensive care - A qualitative, multiformat survey exploring the impact of mandatory oral restriction, from the health care providers perspective.

Intensive Crit Care Nurs

January 2025

Chelsea & Westminster Hospital NHS Foundation Trust, United Kingdom; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, United Kingdom; Division of Anaesthesia, Pain Medicine and Intensive Care (APMIC), Surgery & Cancer, Imperial College London, United Kingdom; Faculty of Medicine, Imperial College London, United Kingdom. Electronic address:

Introduction And Objectives: Nil by mouth (NBM) is a frequent imposition for patients recovering from critical illness. Its impact on patients' wellbeing and rehabilitation is under researched. We sought ICU multidisciplinary opinion to primarily assess the relevance of taste deprivation on patient care and recovery, and to identify future opportunities for innovation and research.

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