Phytotoxicity, microbial activity, plant uptake and microbial degradation were examined using Rumex crispus in TNT and/or cadmium contaminated columns (TNT: 100 mg/kg of soil and Cd: 10 mg/kg of soil). The growth of plants was significantly inhibited by TNT, but not by Cd. The microbial activity was highly increased by plant root growth, decreased by Cd, and slightly reduced by TNT. The plant uptake of Cd was relatively well in Cd-contaminated column, but lowered by TNT in TNT+Cd-contaminated column. The microbial degradation of TNT occurred much faster in planted columns than in unplanted columns with minor effect of Cd (less 2-ADNT was produced). Therefore, it may be effective to treat TNT first and then Cd using phytoremediation in the TNT plus Cd contaminated sites.
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Front Immunol
January 2025
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Mycophenolate mofetil (MMF) is an immunosuppressive drug administered in the management of both autoimmune diseases and organ transplantation. The main aims of the study were: (a) to obtain information regarding the safety of using MMF in respect of its effect on normal T and B cells in lymphoid tissues; (b) to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF.
Methods: The effect of MMF ( studies) and its active metabolite, mycophenolic acid, ( studies) on murine CD4 and CD8 T cells as well as B cells was determined, regarding: (a) absolute count, proliferation and apoptosis of these cells ( studies); (b) absolute count of these cells in the head and neck lymph nodes, mesenteric lymph nodes and the spleen ( studies).
ScientificWorldJournal
January 2025
Department of Biology, College of Science, Bahir Dar University, P. O. Box 79, Bahir Dar, Ethiopia.
The present study was aimed to verify the medicinal value of and traditionally used to treat human and animal ailments in Ethiopia. Fresh leaves of these species were collected, dried under shade, and ground into fine powder. The extraction was carried out by the maceration method using methanol as a solvent.
View Article and Find Full Text PDFThe plant shikimate pathway directs a significant portion of photosynthetically assimilated carbon into the downstream biosynthetic pathways of aromatic amino acids (AAA) and aromatic natural products. 3-Deoxy-d--heptulosonate 7-phosphate (DAHP) synthase (hereafter DHS) catalyzes the first step of the shikimate pathway, playing a critical role in controlling the carbon flux from central carbon metabolism into the AAA biosynthesis. Previous biochemical studies suggested the presence of manganese- and cobalt-dependent DHS enzymes (DHS-Mn and DHS-Co, respectively) in various plant species.
View Article and Find Full Text PDFFront Microbiol
January 2025
Cellular and Organismic Networks, Faculty of Biology, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Introduction: The global decline in biodiversity and insect populations highlights the urgent need to conserve ecosystem functions, such as plant pollination by solitary bees. Human activities, particularly agricultural intensification, pose significant threats to these essential services. Changes in land use alter resource and nest site availability, pesticide exposure and other factors impacting the richness, diversity, and health of solitary bee species.
View Article and Find Full Text PDFFront Microbiol
January 2025
Liaoning Academy of Agricultural Sciences, Shenyang, China.
Purpose: In order to investigate the effects of a rice-crab coculture mode and its duration on the richness and diversity of the soil microbial community.
Method: Soil from long-term rice-crab coculture mode (MY), newly established rice-crab coculture mode (OY) and rice monoculture mode (N) were used to measured soil physicochemical properties, enzyme activity and 16S and ITS soil microbial communities.
Results: The results revealed that in terms of mode, the MBC, MBN and CAT of OY were significantly greater than those of N by 10.
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