Objective: To compare the rate of ectopic pregnancy (EP) with fresh versus frozen blastocyst transfer in our program during the same time period.
Design: Retrospective analysis.
Setting: University IVF program.
Patient(s): Women who achieved a clinical pregnancy after IVF between 1998 and 2005.
Intervention(s): In our program, cryopreservation is performed at the blastocyst stage. Embryo transfer was performed 1 to 1.5 cm short of the fundus by abdominal ultrasound guidance.
Main Outcome Measure(s): The incidence of EP was examined in relation to fresh versus frozen blastocyst transfer.
Result(s): In the frozen blastocyst group, there were 5 EPs out of 180 clinical pregnancies (2.8%), and there were 10 EPs out of 564 clinical pregnancies (1.8%) in the fresh blastocyst group.
Conclusion(s): The rate of EP is not significantly increased after the transfer of frozen thawed blastocysts compared with fresh blastocyst transfer.
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