Frequency-selective quantitation of short-echo time 1H magnetic resonance spectra.

J Magn Reson

Department of Electrical Engineering, SCD-SISTA, Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium.

Published: June 2007

Accurate and efficient filtering techniques are required to suppress large nuisance components present in short-echo time magnetic resonance (MR) spectra. This paper discusses two powerful filtering techniques used in long-echo time MR spectral quantitation, the maximum-phase FIR filter (MP-FIR) and the Hankel-Lanczos Singular Value Decomposition with Partial ReOrthogonalization (HLSVD-PRO), and shows that they can be applied to their more complex short-echo time spectral counterparts. Both filters are validated and compared through extensive simulations. Their properties are discussed. In particular, the capability of MP-FIR for dealing with macromolecular components is emphasized. Although this property does not make a large difference for long-echo time MR spectra, it can be important when quantifying short-echo time spectra.

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http://dx.doi.org/10.1016/j.jmr.2007.03.015DOI Listing

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