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Trajectories and predictors of maternal eating behaviors across the first year postpartum: The role of women's childhood trauma in emotional, external and restraint eating.
Eat Behav
January 2025
Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA.
The first year postpartum is a sensitive time for maternal eating behaviors including emotional, external and restrained eating, which have all been associated with negative health outcomes. Furthermore, among women with a history of trauma, the stress of the postpartum period and early parenting may replicate feelings of helplessness and overwhelm experienced during childhood trauma, which may further contribute to these eating behaviors. Although evidence has shown how mothers eat during this time has long-term implications for infants' eating and health, limited research has characterized eating trajectories and associations with women's history of childhood trauma exposure during this critical period.
View Article and Find Full Text PDFOxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder.
Front Biosci (Landmark Ed)
January 2025
HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged (HUN-REN-SZTE), Danube Neuroscience Research Laboratory, H-6725 Szeged, Hungary.
Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT) metabolism. Over 90% of the 5-HT precursor tryptophan (Trp) is metabolized via the Trp-kynurenine (KYN) metabolic pathway, which generates a variety of bioactive molecules. Dysregulation of KYN metabolism, particularly low levels of kynurenic acid (KYNA), appears to be linked to neuropsychiatric disorders.
View Article and Find Full Text PDFPsychosocial problems observed in older adults after disaster.
Psychogeriatrics
March 2025
Faculty of Health Sciences, Department of Psychiatric Nursing, Gaziantep University, Gaziantep, Turkey.
Natural disasters are large-scale catastrophic events that seriously disrupt the functioning of a community or society. The frequency and severity of disasters are increasing and involve widespread human, material, economic, or environmental impacts that exceed the ability of the society affected by them to cope using its resources. In addition, disasters significantly affect the physical, emotional, and psychological health of individuals and cause numerous deaths, injuries, and economic losses.
View Article and Find Full Text PDFUnraveling the neuroprotective effect of perampanel and lacosamide combination in the corneal kindling model for epilepsy in mice.
Animal Model Exp Med
January 2025
Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Background: Scientific evidence to guide clinicians on the use of different antiseizure drugs in combination therapy is either very limited or lacking. In this study, the impact of lacosamide and perampanel alone and in combination was tested in corneal kindling model in mice, which is a cost-effective mechanism for screening of antiseizure drugs.
Methods: The impact of lacosamide (5 mg/kg) and perampanel (0.
Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems.
Front Psychol
January 2025
Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy.
Depression is presented as a multi-factorial bio-psycho-social expression that has evolved primarily as an effect of stressors related to the motivational/emotional systems that regulate the in our relationship with conspecifics. These stressors may be caused by two sources of threat, firstly, the loss of bonding with the caregiver and later with a partner and/or group which relates to the SEPARATION (PANIC/GRIEF) system, secondly, social defeat as an expression of the social competition and social dominance. The sexual maturity drives the individual to social competition and social dominance, even if the latter often occurs before sexual maturity, e.
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