Authors replaced the esophagus with anisoperistaltic left colon because they had no other possibilities. In this case twenty-one years ago after an esophageal injury the patient underwent gastric resection, removal of the esophagus and replacement with a skin tube created from a myocutaneous flap. Unfortunately the right colon earlier had been removed after an unsuccessful replacement. Twenty-one years later carcinoma developed in the skin tube therefore the tumour was removed and anisoperistaltic left colon was used as a "new esophagus". The pulled up left colon was supplied by the left colic artery and supercharged by a vascular anastomosis on the neck. Authors would like to present that esophageal replacement with anisoperistaltic left colon is a feasible method if no other therapeutic option remains.
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