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Dapagliflozin and Right Ventricular-Pulmonary Vascular Interaction in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of a Randomized Clinical Trial.
JAMA Cardiol
September 2024
Department of Cardiovascular Medicine, Mayo Clinic and Foundation, Rochester, Minnesota.
Importance: Increases in pulmonary capillary wedge pressure (PCWP) during exercise reduce pulmonary artery (PA) compliance, increase pulsatile right ventricular (RV) afterload, and impair RV-PA coupling in patients with heart failure with preserved ejection fraction (HFpEF). The effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin on pulmonary vascular properties and RV-PA coupling are unknown.
Objective: To test the effect of dapagliflozin on right ventricular performance and pulmonary vascular load during exertion in HFpEF.
Why women deserve special attention during exercise in hot environments: a commentary.
J Appl Physiol (1985)
June 2024
Department of Biophysics and Physiology, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Percentage of Peak Workload Is Suitable for Quantification of Exercise Intensity During High-Intensity Intervals: A Comment on Ekkekakis, Hartman, and Ladwig.
J Sport Exerc Psychol
April 2024
School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
Lower Leg Lateral Chronic Exertional Compartment Syndrome: Prospective Surgical Treatment Outcomes for Isolated or Combined Lateral Fasciotomy.
Foot Ankle Int
November 2023
Department of Surgery, Máxima Medical Center, Eindhoven/Veldhoven, the Netherlands.
Background: Chronic exertional compartment syndrome involving the lower leg lateral compartment (lat-CECS) seldom occurs isolated but is usually combined with CECS of the anterior (ant-CECS) or deep posterior compartment (dp-CECS). Patient characteristics in lat-CECS and outcome after surgery are largely unknown. The aim of this prospective case series was to describe patient characteristics and symptoms and to report on outcome following a fasciotomy.
View Article and Find Full Text PDFUnrepaired tetralogy of Fallot in a 71 years old woman: A case report and review of the literature.
Echocardiography
November 2023
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease (CHD) in infants. The four components that constitute ToF are an overriding aorta over the crest of the interventricular septum, obstruction in the right ventricular outflow tract, right ventricular hypertrophy, and a typically large non-restricted ventricular septal defect. ToF may also be associated with other extracardiac abnormalities, including patent ductus arteriosus or multiple aortopulmonary collateral arteries, which can impact the patient's survival.
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