Purpose: The purpose of this article is to present definitions and concepts about sensory modulation, illustrate behavioral aspects of sensory modulation disorders, describe a framework for assessment and intervention, and present advances in research.
Method: A review of descriptive and evidence-based literature related to the impact of exposure to both prenatal and postnatal trauma on sensory modulation is provided, with additional information gleaned from recent assessment data on children with a history of trauma who are served by the Southwest Michigan Children's Trauma Assessment Center (CTAC).
Clinical Implications: The review of the literature indicates support for the presence of sensory modulation disorders among traumatized children. In addition, the emerging data now being gathered on children who have been assessed by CTAC indicate a significant prevalence of sensory modulation disorders among children with a history of trauma alone, and those with both trauma and a diagnosis of fetal alcohol spectrum disorder (FASD). Awareness, recognition, and identification of behaviors associated with this disorder, and referral to appropriate professionals, is essential to ensure effective preventive and intervention services.
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http://dx.doi.org/10.1044/0161-1461(2007/011) | DOI Listing |
Front Aging Neurosci
January 2025
Department of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, China.
Background And Purpose: Asymptomatic carotid stenosis (ACS) is an independent risk factor for ischemic stroke and vascular cognitive impairment, affecting cognitive function across multiple domains. This study aimed to explore differences in static and dynamic intrinsic functional connectivity and temporal dynamics between patients with ACS and those without carotid stenosis.
Methods: We recruited 30 patients with unilateral moderate-to-severe (stenosis ≥ 50%) ACS and 30 demographically-matched healthy controls.
Myoelectric prosthetic hands are typically controlled to move between discrete positions and do not provide sensory feedback to the user. In this work, we present and evaluate a closed-loop, continuous myoelectric prosthetic hand controller, that can continuously control the position of multiple degrees of freedom of a prosthesis while rendering proprioceptive feedback to the user via a haptic feedback armband. Twenty-eight participants without and ten participants with upper limb difference (ULD) were recruited to holistically evaluate the physical and psychological effects of the controller via isolated control and sensory tasks, dexterity assessments, embodiment and task load questionnaires, and post-study interviews.
View Article and Find Full Text PDFBehav Brain Res
January 2025
Laboratorio de Neurociencias, Facultad de Psicología, Universidad de Colima, Colima, Mexico 28040. Electronic address:
Tactile information from the whiskers (vibrissae) travels through the somatosensory cortex to the entorhinal cortex and the hippocampus, influencing development and psychological well-being. The lack of whiskers affects cognitive functions, spatial memory, neuronal firing, spatial mapping, and neurogenesis in the dorsal hippocampus. Recent studies underline the importance of tactile experiences in emotional health, noting that while tactile stimuli modulate the dorsal hippocampus, the effects of tactile deprivation on anxiety-like behaviors and neural activity in regions like the ventral hippocampus and amygdala are less understood.
View Article and Find Full Text PDFAging Cell
January 2025
Molecular Biology and Genetics Unit, Transcription and Disease Laboratory, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India.
SYNGAP1 is a Ras GTPase-activating protein that plays a crucial role during brain development and in synaptic plasticity. Sporadic heterozygous mutations in SYNGAP1 affect social and emotional behaviour observed in intellectual disability (ID) and autism spectrum disorder (ASD). Although neurophysiological deficits have been extensively studied, the epigenetic landscape of SYNGAP1 mutation-mediated intellectual disability is unexplored.
View Article and Find Full Text PDFFront Immunol
January 2025
National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
Bacterial meningitis is a severe and life-threatening infection of the central nervous system (CNS), primarily caused by and . This condition carries a high risk of mortality and severe neurological sequelae, such as cognitive impairment and epilepsy. Pain, a central feature of meningitis, results from the activation of nociceptor sensory neurons by inflammatory mediators or bacterial toxins.
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