The incorporation of multiple antigens into a single human papillomavirus (HPV) vaccine may induce immune interference. To evaluate whether interference occurs when HPV type 16 (HPV16) virus-like particles are combined in a multivalent vaccine, we conducted a study to evaluate anti-HPV16 responses among subjects receiving three-dose regimens of either a monovalent HPV16 vaccine or a quadrivalent HPV (types 6, 11, 16, and 18) vaccine.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951095 | PMC |
| http://dx.doi.org/10.1128/CVI.00478-06 | DOI Listing |
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