Objectives: Measurement of cortical thickness and subjective assessment of cortical porosity on panoramic radiographs are methods previously reported for diagnosing osteoporosis. The aims of this study were to determine the relative efficacy of the mandibular cortical index and cortical width in detecting osteoporosis, both alone and in combination, and to determine the optimal cortical width threshold for referral for additional osteoporosis investigation.

Study Design: Six hundred seventy-one postmenopausal women 45 to 70 years of age were recruited for this study. They received dual energy x-ray absorptiometry (DXA) scans of the left hip and lumbar spine (L1 to L4), and dental panoramic radiographic examinations of the teeth and jaws. Three observers separately assessed the mandibular cortical width and porosity in the mental foramen region of the mandible. Cortical width was corrected for magnification errors. Chi-squared automatic interaction detection analysis (CHAID) software was used (SPSS AnswerTree, version 3.1, SPSS Inc., Chicago, IL).

Results: Chi-squared automatic interaction detection analysis showed that the cortical porosity was a poorer predictor of osteoporosis than mandibular cortical width. For the 3 observers, a mandibular cortical width of <3 mm provided diagnostic odds ratios of 6.51, 6.09, and 8.04. The test is therefore only recommended in triage screening of individuals by using radiographs made for purposes other than osteoporosis.

Conclusion: When evaluating panoramic radiographs, only those patients with the thinnest mandibular cortices (i.e., <3 mm) should be referred for further osteoporosis investigation.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tripleo.2006.12.027DOI Listing

Publication Analysis

Top Keywords

cortical width
24
mandibular cortical
16
cortical
10
diagnosing osteoporosis
8
dental panoramic
8
panoramic radiographs
8
cortical porosity
8
chi-squared automatic
8
automatic interaction
8
interaction detection
8

Similar Publications

Objectives: To explore the neuroprotective mechanism of electroacupuncture at the acupoints and in rats with cerebral ischemia-reperfusion (IR) injury.

Methods: Forty-eight male SD rats were equally randomized into sham operation group, cerebral IR model group, acupoint electroacupuncture group and non-acupoint acupuncture group. In the latter 3 groups, cerebral focal ischemic injury was induced using the Longa method; in the two electroacupuncture groups, electroacupuncture was performed either at the acupoints and or at non-acupoint sites for 7 days.

View Article and Find Full Text PDF

In functional magnetic resonance imaging, the hemodynamic response function (HRF) is a stereotypical response to local changes in cerebral hemodynamics and oxygen metabolism due to briefly (< 4 s) evoked neural activity. Accordingly, the HRF is often used as an impulse response with the assumption of linearity in data analysis. In cognitive aging studies, it has been very common to interpret differences in brain activation as age-related changes in neural activity.

View Article and Find Full Text PDF

Background: The accessory mental foramen is characterized by small foramina in the surrounding area of the mental foramen with communication with the mandibular canal. The aim of this research was to evaluate epidemiological and radiomorphometric aspects of the accessory mental foramen (AMF) using cone beam computed tomography (CBCT) in Brazilian individuals.

Material And Methods: This was a cross-sectional, quantitative, retrospective descriptive study with 250 CBCT scans of dentate individuals in the anterior mandibular region, aged between 18 and 69 years.

View Article and Find Full Text PDF

Introduction: This study aimed to assess the impact of midline lumbar fusion with cortical bone trajectory screws (MIDLF/CBT) on the multifidus muscles, focusing on the evaluation of their postoperative atrophy.

Clinical Rationale For The Study: MIDLF/CBT is a relatively new technique increasingly used to treat spinal instability. Despite its reduced invasiveness compared to traditional posterior lumbar interbody fusion with traditional pedicle screws (PLIF/TP), concerns remain about potential damage to the multifidus muscles that are crucial for spinal stability.

View Article and Find Full Text PDF

The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function.

Acta Neuropathol Commun

December 2024

The Key Laboratory of Experimental Teratology of the Ministry of Education and Department of Genetics, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Article Synopsis
  • Cullin 4B (CUL4B) is a protein linked to X-linked intellectual disability (XLID), with its mutations leading to brain dysfunction and impaired cognition.
  • Researchers used advanced single-nucleus RNA sequencing to study how CUL4B deficiency affects communication and gene expression among different brain cell types, finding significant changes that relate to synapse problems.
  • The study demonstrated that CUL4B-deficient mice exhibited synapse loss, abnormal synaptic structures, and decreased memory capabilities, highlighting the potential for targeted therapies to address synaptic issues and cognitive decline related to CUL4B mutations.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!