The ACLAM Analgesia Task Force was appointed by ACLAM President Diane Gaertner in 2003. The charge to the Task Force was to develop guidelines that could be used by veterinarians, scientists and IACUCs in helping to provide appropriate assessment and management of pain in rodents, with the understanding that ultimately the clinical veterinarian on site at the institution must make decisions relevant to a specific animal or animals and/or protocol. The guidelines were not to be developed as, and should not be used as, requirements. To complete its charge the Task Force reviewed and cited, in a comprehensive manner, available data-based literature in writing the paper. In the course of completion of the document, ACLAM Board of Directors (BOD) reviewed an early draft and at that time also appointed 3 ACLAM diplomates with particular expertise in assessment and management of pain in rodents to act as reviewers of the draft. The Task Force members responded to the critiques and comments submitted by both the BOD and the 3 reviewers. This revised draft was then placed on the ACLAM website for comments from the entire College. The draft was well received by responding diplomates. Comments from the membership were reviewed and discussed by the Task Force, and most were incorporated into the final draft manuscript. The draft then received final review and editing by the ACLAM Publications Committee Chairman, and was accepted in the format presented here. Despite this extensive vetting process through ACLAM, readers should nonetheless be aware that because this document represents the approved statement of an AALAS affiliate organization, it has not undergone the usual JAALAS peer review process. I would like to acknowledge the efforts of the Task Force and the leadership of ACLAM for supporting this comprehensive and informative synthesis. The document should serve as a resource to the research community for years to come.
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Sci Rep
December 2024
Department of Public Health, College of Life Sciences, Brigham Young University, 2063 Life Sciences Building, Provo, UT, 84602, USA.
The prevalence of prostate-specific antigen (PSA) testing has consistently fallen for several years. This study explored how the decreasing trend differs by selected variables and reasons for taking the PSA test. Analyses involved men, aged 40 years or older, who completed the Behavior Risk Factor Surveillance System (BRFSS) survey in even number years from 2008 through 2022.
View Article and Find Full Text PDFPituitary
December 2024
Department of Endocrinology and Nutrition, Hospital Universitario de Puerta de Hierro Majadahonda, Madrid, Spain.
Purpose: Studies focused on the effects of sellar and/or perisellar (S/PS) meningiomas on pituitary function are scarce. The primary objective of the present study was to determinate the effects that S/PS meningiomas and their treatments have on pituitary function. Also, we described the clinical characteristics and therapeutic outcomes of the cohort of adult Spanish patients.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841 S Maryland Ave, Chicago, IL, 60637, USA.
Psychoactive drugs such as alcohol and stimulants are typically used in social settings such as bars, parties or small groups. Yet, relatively little is known about how social contexts affect responses to drugs, or how the drugs alter social interactions. It is possible that positive social contexts enhance the rewarding properties of drugs, perhaps increasing their potential for repeated use and abuse.
View Article and Find Full Text PDFBMJ Open
December 2024
Eyu-Ethiopia: Eye Health Research, Training & Service Centre, Bahir Dar, Ethiopia
Introduction: The WHO neglected tropical diseases (NTD) roadmap (2021-2030) proposed a shift in approach to addressing NTDs through accountability for impact, implementing integration across NTDs, mainstreaming in national health systems and ensuring country ownership. However, a major challenge has been the dearth of evidence on how to implement this shift in a resource-limited setting. The objective of this scoping review is to understand the extent and type of evidence on the mainstreaming or integration of programmes and/or interventions against NTDs into the national health system.
View Article and Find Full Text PDFJ Clin Epidemiol
December 2024
Department of Internal Medicine, American University of Beirut, Beirut, Lebanon; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Objective: To describe the processes of reconciling overlapping guidance and prioritizing practice questions for a World Health Organization (WHO) guideline on Infection Prevention and Control (IPC) for Ebola and Marburg disease.
Methods: This work involved the reconciliation of guidance, the generation of potential practice questions and the prioritization of those questions. Contributors included the WHO secretariat, the WHO steering group, the guideline methodologists, and the guideline development group (GDG).
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