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http://dx.doi.org/10.2146/ajhp070139 | DOI Listing |
Biol Direct
January 2025
School of Medicine, South China University of Technology, Guangzhou, 510006, China.
Background: Pancreatic cancer is characterized by a complex tumor microenvironment that hinders effective immunotherapy. Identifying key factors that regulate the immunosuppressive landscape is crucial for improving treatment strategies.
Methods: We constructed a prognostic and risk assessment model for pancreatic cancer using 101 machine learning algorithms, identifying OSBPL3 as a key gene associated with disease progression and prognosis.
Biotechnol Biofuels Bioprod
January 2025
Section II: Electrobiotechnology, Institute of Process Engineering in Life Science, Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany.
Background: Parageobacillus thermoglucosidasius is a facultatively anaerobic thermophile that is able to produce hydrogen (H) gas from the oxidation of carbon monoxide through the water-gas shift reaction when grown under anaerobic conditions. The water-gas shift (WGS) reaction is driven by a carbon monoxide dehydrogenase-hydrogenase enzyme complex. Previous experiments exploring hydrogenogenesis with P.
View Article and Find Full Text PDFInt J Equity Health
January 2025
Tekano, Capetown, South Africa.
Globally, individuals with Down syndrome (DS) face profound inequities in social and health care access. These challenges are further compounded by racial disparities as well as a lack of awareness, research, and support, particularly in the Global South. This commentary discusses the multifaceted challenges and disparities encountered by people with DS in South Africa, highlighting the need for targeted interventions.
View Article and Find Full Text PDFBMC Nurs
January 2025
Student research committee, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Intensive care unit (ICU) nurses work under heavy workloads, which can lead to serious consequences for nurses' outcomes and patient safety. This study aimed to examine the relationship between professional quality of life (Pro QOL), and sleep quality among ICU nurses during the COVID-19 outbreak.
Methods: A cross-sectional and multicentre study was conducted on 253 nurses in 20 COVID-19 ICUs in four major teaching hospitals from July 2021 to June 2022.
BMC Nurs
January 2025
Department of Healthcare Management Research Center, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Aim: This study aimed to explore the emotions of operating room nurses in Japan towards perioperative nursing using generative AI and human analysis, and to identify factors contributing to burnout and turnover.
Methods: A single-center cross-sectional study was conducted from February 2023 to February 2024, involving semi-structured interviews with 10 operating room nurses from a national hospital in Japan. Interview transcripts were analyzed using generative AI (ChatGPT-4o) and human researchers for thematic, emotional, and subjectivity analysis.
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