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Severe human metapneumovirus infection in hospitalized children. | LitMetric

Severe human metapneumovirus infection in hospitalized children.

Clin Pediatr (Phila)

Division of Pediatric Infectious Diseases, University of South Alabama, Mobile, Alabama 36604, SUA. bestrada@ usouthal.edu

Published: April 2007

AI Article Synopsis

  • Human metapneumovirus causes respiratory infections in children, with a recent study observing 11 hospitalized cases over 6 months.
  • A significant 82% of patients needed oxygen, and 45% experienced severe illness requiring mechanical ventilation.
  • Children with pre-existing conditions like asthma or neuromuscular diseases faced longer hospital stays due to this infection.

Article Abstract

Human metapneumovirus is a recently discovered pathogen that causes upper and lower respiratory tract disease in children. This study describes the course of illness in hospitalized children with this infection. During a 6-month period, 11 children were diagnosed with human metapneumovirus infection by reverse transcription-polymerase chain reaction. Oxygen supplementation was required for 82% of patients. Severe disease developed in 45%, and mechanical ventilation was required. An apparent life-threatening event was the indication for hospitalization of 27% of patients infected with human metapneumovirus. Children with underlying asthma or neuromuscular disease had a prolonged hospitalization.

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Source
http://dx.doi.org/10.1177/0009922806293896DOI Listing

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