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Flexible Triboelectric Nanogenerator Patch for Accelerated Wound Healing Through the Synergy of Electrostimulation and Photothermal Effect.
Small
January 2025
Guangzhou Institute of Blue Energy, Knowledge City, Huangpu District, Guangzhou, 510555, P. R. China.
Physiological wound healing process can restore the functional and structural integrity of skin, but is often delayed due to external disturbance. The development of methods for promoting the repair process of skin wounds represents a highly desired and challenging goal. Here, a flexible, self-powered, and multifunctional triboelectric nanogenerator (TENG) wound patch (e-patch) is presented for accelerating wound healing through the synergy of electrostimulation and photothermal effect.
View Article and Find Full Text PDFThe formation, maintenance, and loss of island biodiversity.
Yi Chuan
January 2025
Center for Global Change and Ecological Forecasting, Zhejiang Zhoushan Island Ecosystem Observation and Research Station, Institute of Eco-Chongming, Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, School of Ecological and Environmental Sciences, East China Normal University, Shanghai 200241, China.
Due to the unique geographical features of large numbers, isolated by water and diverse formation histories, islands have become natural laboratories for ecological and evolutionary research. Islands have a high proportion of endemic species and disharmony in representing the species compared with that in the continent, which provides a good opportunity to explore the formation of island biodiversity. In this review, we focuse on island ecosystems and describes the progress of research in island biogeography in recent years from three aspects: formation, maintenance, and loss of island biodiversity.
View Article and Find Full Text PDFEmerging Violet Phosphorus Nanomaterial for Biomedical Applications.
Adv Healthc Mater
January 2025
State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing, 211198, P. R. China.
Violet phosphorus (VP) is a phosphorus allotrope first discovered by Hittorf in 1865, which has aroused more attention in the biomedical field in recent years attributed to its gradually discovered unique properties. VP can be further categorized into bulk VP, VP nanosheets (VPNs), and VP quantum dots (VPQDs), and chemical vapor transport (CVT), liquid-phase/mechanical/laser exfoliation, and solvothermal synthesis are the common preparation approaches of bulk VP, VPNs, and VPQDs, respectively. Compared with another phosphorus allotrope (black phosphorus, BP) that is once highly regarded in biomedical applications, VP nanomaterial (namely VPNs and VPQDs) not only exhibits tunable bandgap, moderate on/off current ratio, and good biodegradability, but shows enhanced stability and biosafety as well, allowing it to be a promising candidate for a variety of biomedical applications like antibacterial therapy, anticancer therapy, and biosensing and disease diagnosis.
View Article and Find Full Text PDFMeasuring Self-Reported Well-Being of Physicians Using the Well-Being Thermometer: Cohort Study.
JMIR Form Res
January 2025
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Background: Advancements in medical science have focused largely on patient care, often overlooking the well-being of health care professionals (HCPs). This oversight has consequences; not only are HCPs prone to mental and physical health challenges, but the quality of patient care may also endure as a result. Such concerns are also exacerbated by unprecedented crises like the COVID-19 pandemic.
View Article and Find Full Text PDFBiomimetic Diselenide-Sonosensitizer Nanoplatform for Enhanced Sonodynamic Therapy and In Situ Remodeling Immunosuppressive Microenvironment via Activating Innate and Adaptive Immunotherapy.
Adv Healthc Mater
January 2025
School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Sonodynamic therapy (SDT), which is non-invasive and controllable has the potential to treat triple-negative breast cancer (TNBC). However, the hypoxia and immunosuppressive tumor microenvironment (TME) often block the production of reactive oxygen species and the induction of SDT-activated immunogenic cell death, thus limiting the activation of adaptive immune responses. To alleviate these challenges, we proposed the development of a multifunctional biomimetic nanoplatform (mTSeIR), which was designed with diselenide-conjugated sonosensitizers and tirapazamine (TPZ), encapsulated within M1 macrophage membrane.
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