Food protein-induced enterocolitis syndrome is a severe cell-mediated, non-immunoglobulin E-mediated gastrointestinal food allergy, typically to milk and soy. It may masquerade as more common pediatric presentations, where the temporal relationship between symptomatology and exposure to food offers a vital clue to the underlying pathology. A case of food protein-induced enterocolitis syndrome presenting with features similar to intussusception, leading to unnecessary surgery, is presented.
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Severity trend of recurrence in pediatric Food Protein-Induced Enterocolitis Syndrome (FPIES).
J Allergy Clin Immunol Pract
January 2025
Pediatric Allergy Unit, Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University of the Sacred Heart, 00168 Rome, Italy. Electronic address:
Background: Reintroduction of offending food in pediatric patients affected by Food Protein-Induced Enterocolitis Syndrome (FPIES) is carried out in hospitals with Oral Food Challenge (OFC), which leads to long waiting time and increases the societal burden of medical cost and human resources.
Objective: The aim of the study is to assess severity trend of acute FPIES adverse reactions over time in the same patient for possible outpatient or home reintroduction of offending food.
Methods: All children (<18 years-old) with a diagnosis of acute FPIES referred to 2 Italian pediatric allergy clinics were retrospectively enrolled.
Measurement of Fecal Calprotectin and Zonulin as Biomarkers in Adults With Fish-Induced Food Protein-Induced Enterocolitis Syndrome.
J Investig Allergol Clin Immunol
January 2025
Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Association between body mass index at birth and neonatal health outcomes in preterm infants: A retrospective analysis.
Pediatr Obes
January 2025
Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Background: Studies on how birth body mass index (BMI) affects health outcomes in preterm infants are relatively limited.
Aim: To analyze the association between BMI at birth and neonatal health outcomes in extremely low and very low birth weight preterm infants in China.
Methods: Used data from the Chinese Premature Infant Informatization Platform (2022-2023).
Development of a Buckwheat Allergy in a Child During Food Protein-Induced Enterocolitis Syndrome Due to Hen's Egg: A Case Report.
Cureus
December 2024
Department of Pediatrics, IMS Group, IMS Memorial Hospital, Tokyo, JPN.
Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE)-mediated food allergy. IgE sensitization to the causative food is often not observed, and the rate of sensitization to other common foods is not exceptionally high. This report discusses the case of a boy being followed up for FPIES due to egg yolk, who developed a buckwheat allergy during the disease.
View Article and Find Full Text PDFDrug-induced enterocolitis, a new condition under consideration.
Allergol Immunopathol (Madr)
January 2025
Pediatric Allergy and Pulmonology Unit, Children's University Hospital Reina Sofia, Cordoba, Spain;
Drug-induced enterocolitis syndrome (DIES), little known due to its recent description, is analogous to food protein-induced enterocolitis syndrome (FPIES). Both processes are more frequent in pediatric age and share diagnostic criteria, the main one being the appearance of persistent vomiting 1-4 hours after ingestion of the drug or food, in the absence of IgE-mediated allergy symptoms.
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