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Examining Concurrent Associations Between Gesture Use, Developmental Domains, and Autistic Traits in Toddlers With Down Syndrome.
J Speech Lang Hear Res
January 2025
Down Syndrome Program, Division of Developmental Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, MA.
Purpose: Toddlers with Down syndrome (DS) showcase comparable or higher rates of gestures than chronological age- and language-matched toddlers without DS. Little is known about how gesture use in toddlers with DS relates to multiple domains of development, including motor, pragmatics, language, and visual reception (VR) skills. Unexplored is whether gesture use is a good marker of social communication skills in DS or if gesture development might be more reliably a marker of motor, language, pragmatics, or VR skills.
View Article and Find Full Text PDFDecoding brain structure to stage Alzheimer's disease pathology in Down syndrome.
Alzheimers Dement
January 2025
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.
Introduction: Alzheimer's disease (AD) in Down syndrome (DS) is associated with changes in brain structure. It is unknown if thickness and volumetric changes can identify AD stages and if they are similar to other genetic forms of AD.
Methods: Magnetic resonance imaging scans were collected for 178 DS adults (106 nonclinical, 45 preclinical, and 27 symptomatic).
AEQUANIMITAS FOR OUR TIME.
Am J Med
December 2024
Executive Vice President, USF Health, Dean, USF Health Morsani College of Medicine, 12901 Bruce B. Downs Blvd., MDC02, Tampa, FL, 33612. Electronic address:
Music to Their Ears: Reducing Antipsychotic Use With a Personalized Music Intervention for Rural Veterans.
Cureus
November 2024
Psychology, Lexington Veterans Affairs Health Care System, Lexington, USA.
Background This project investigates a music intervention to deprescribe antipsychotics in rural Veterans with dementia. Methods The Veterans Health Administration Home-Based Primary Care Program is care provided in the home by an interdisciplinary team with the goals of decreasing hospitalizations and falls, providing education to patients and caregivers, and improving quality of life. Eighteen Home Based Primary Care Veterans with dementia and active antipsychotic prescriptions were identified with the goal to deprescribe antipsychotics in 50% of them using a music intervention.
View Article and Find Full Text PDFClimate-driven global redistribution of an ocean giant predicts increased threat from shipping.
Nat Clim Chang
October 2024
Marine Biological Association, The Laboratory, Plymouth, UK.
Article Synopsis
- Climate change is causing shifts in animal habitats, particularly affecting the distribution of threatened marine species like whale sharks.
- Projections indicate that by 2100, whale sharks could lose more than 50% of their core habitat in some areas, with significant geographic shifts that could place them in closer proximity to large ships.
- The increase in whale shark interaction with shipping is expected to be dramatically higher under high emission scenarios compared to sustainable development, highlighting the urgency for better climate-threat predictions in conservation strategies for endangered marine life.
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