Seventeen cases of a superficial corneal dystrophy are presented. The lesions are subepithelial, limited mainly to Bowman's layer. This dystrophy, although clinically different from classic granular dystrophy, is pathologically similar to it. Treatment, consisting of superficial keratectomy to 15% to 20% of corneal thickness, did not require lamellar grafting and produced good visual results. A new classification of granular dystrophy is proposed.
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http://dx.doi.org/10.1016/s0161-6420(92)32004-4 | DOI Listing |
Cureus
August 2024
Department of Ophthalmology, Erasmus Hospital, Brussels, BEL.
Corneal dystrophies are a group of rare genetic eye disorders characterized by the accumulation of abnormal material in different layers of the cornea, potentially leading to vision impairment. In vivo confocal microscopy (IVCM) is an emerging non-invasive imaging and diagnostic tool that helps study the ocular surface microstructure. This case report examines the clinical characteristics of Avellino corneal dystrophy in a young patient through the use of slit lamp examination, IVCM, and optical coherence tomography (OCT) in order to assess the effectiveness of these non-invasive tests as diagnostic tools.
View Article and Find Full Text PDFACR Open Rheumatol
October 2024
University of Washington, Seattle, Washington.
Objective: The pathogenesis of inflammatory myopathies is poorly understood and there is a need to dissect the transcriptome in more granular ways beyond gene expression.
Methods: We used a set of muscle RNA-sequencing data from different myositis subtypes grouped by their specific autoantibodies (n = 152). We quantified annotated RNA transcripts for each myositis subtype and identified uniquely expressed RNA as well as transcriptional similarities among myositis types.
Cornea
January 2025
Shantilal Shanghvi Cornea Institute, LV Prasad Eye Institute, Hyderabad, India; and.
Purpose: To report the management of recurrent TGF BI dystrophy after prior femtosecond-assisted anterior lamellar keratoplasty (FALK) with repeat FALK.
Methods: Clinical and histopathological study of 2 eyes of 2 patients with a recurrence of TGFBI dystrophy. Patient 1 had Reis-Buckler corneal dystrophy, and patient 2 had granular corneal dystrophy GCD type 1.
Pharmacol Res Perspect
August 2024
Pfizer Inc, New York, New York, USA.
Mol Vis
April 2024
Department of Biophysics, All India Institute of Medical Sciences, New Delhi.
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