Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1538-7836.2007.02338.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Opioid Overdose in Patients With Concomitant Use of Tramadol and Clopidogrel vs Alternative Antiplatelet Agents.
J Am Coll Cardiol
October 2024
Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
Aspirin Desensitization and Percutaneous Coronary Intervention in a Patient with Aspirin Hypersensitivity and Acute Coronary Syndrome: A Case Report.
JNMA J Nepal Med Assoc
June 2024
Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Kathmandu, Nepal.
Hypersensitivity to aspirin is rare disorder occurring in 1.88% of the patients. Aspirin-hypersensitive patients requiring single antiplatelet agent may be treated with clopidogrel, an alternative antiplatelet agent.
View Article and Find Full Text PDFReal-world evaluation of guided antiplatelet therapy in patients undergoing intracranial aneurysm repair.
Pharmacogenomics
November 2024
Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Article Synopsis
- * A significant portion (25.5%) of patients were identified as intermediate or poor metabolizers (IM/PM), resulting in a higher usage of alternative therapies compared to normal metabolizers.
- * Although the study suggests that pre-emptive genotyping for selecting antiplatelet therapy is effective, further research with larger sample sizes is needed to determine its impact on clinical outcomes.
Aspirin-clopidogrel combination therapy for ischemic stroke patients: Clinical efficacy and cost-effectiveness analyses in low-resource setting.
Narra J
August 2024
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Andalas, Padang, Indonesia.
Understanding the cost-effectiveness of aspirin-clopidogrel combination therapy is crucial in determining its influence on coagulation parameters, specifically prothrombin time (PT) and activated partial thromboplastin time (APTT). The aim of this study was to assess the cost-effectiveness and clinical impact of using the aspirin-clopidogrel combination compared to aspirin alone in managing ischemic stroke. Employing an observational research design, inpatient ischemic stroke cases receiving the aspirin-clopidogrel combination were compared to those treated with aspirin alone.
View Article and Find Full Text PDFClinical and cost-effectiveness of clopidogrel resistance genotype testing after ischaemic stroke or transient ischaemic attack: a systematic review and economic model.
Health Technol Assess
September 2024
Bristol TAG, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Article Synopsis
- Stroke patients on clopidogrel may face risks from genetic variants that impair how their bodies process the medication; genetic testing can help identify these issues for better treatment targeting.* -
- The study examined whether genetic testing for clopidogrel resistance can lead to a lower risk of future vascular events, especially when using alternative medications like ticagrelor instead of clopidogrel.* -
- Results showed that while two studies indicated a reduced risk of events in genetically tested patients, the evidence was not very strong, and ticagrelor was found to be more effective than clopidogrel in those with genetic variants.*
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!