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Investigation of the association between therapeutic effectiveness of anamorelin and Glasgow prognostic score in patients with cancer cachexia: a competing risk analysis.
Invest New Drugs
January 2025
Department of Pharmacy, Aichi Cancer Center Hospital, 1-1, Kanokoden, Chikusa-Ku, Nagoya, Aichi, 464-8681, Japan.
Anamorelin, a highly selective ghrelin receptor agonist, enhances appetite and increases lean body mass in patients with cancer cachexia. However, the predictors of its therapeutic effectiveness are uncertain. This study aimed to investigate the association between the Glasgow prognostic score (GPS), used for classifying the severity of cancer cachexia, the therapeutic effectiveness of anamorelin, and the feasibility of early treatment based on cancer types.
View Article and Find Full Text PDFPatients' Use of e-Consultations as an Alternative to Other General Practitioner Services: Cross-Sectional Survey Study.
J Med Internet Res
January 2025
Norwegian Centre for E-health Research, University Hospital of North Norway, Tromsø, Norway.
Background: e-Consultations, defined as asynchronous text-based messaging, have transformed how patients interact with their general practitioner (GP). While e-consultations can improve patient access to GP care, concerns about increased workload for GPs are raised.
Objective: This study aimed to address three research questions: (1) For what purpose and with what expectations do patients initiate e-consultations? (2) If e-consultations had not been available, what alternative actions would the patient have taken? and (3) How are the alternative actions associated with patient and e-consultation characteristics?
Methods: A cross-sectional study was conducted through a web-based survey on Helsenorge.
Predictive factors for the diagnosis of coeliac disease in children and young people in primary care: A systematic review and meta-analysis.
PLoS One
December 2024
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Background: Coeliac Disease (CD) often has its onset in childhood and affects 1% of the population. This review aimed to identify important predictive factors for coeliac disease in children and young people which could help GPs decide when to offer testing.
Methods: We searched MEDLINE, Embase and Cochrane Library to April 2024.
A Survey Among General Practitioners and Periodontal Specialists in Norway Documenting a Positive Attitude Towards Guideline-Based Referral Practise.
J Clin Periodontol
December 2024
Faculty of Medicine, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.
Aim: The objective of this cross-sectional survey was to assess the attitude among general practitioners (GPs) and periodontal specialists (PSs) in Norway towards developing and implementing guideline-based periodontal referral practise.
Material And Methods: A multiple-choice questionnaire was distributed online to a sample of professionally active GPs and PSs. The survey included questions on demographics, practise profile, proficiency and insight among oral healthcare providers, periodontal referral patterns, and attitude on establishing guideline-based referral practise.
Primary Care Referral Delays in Oral Cancer Diagnosis: A Meta-Analysis.
Oral Dis
December 2024
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBER-ESP), Madrid, Spain.
Objective: To measure the primary care interval (PCI) in the diagnostic delay of oral cancer and to assess the relation of the referring physician's specialty with disease stage at diagnosis.
Methods: We meta-analyzed reports of oral/oropharyngeal carcinomas detailing PCI start- and endpoints, i.e.
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