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Dispelling Myths and Unfounded Practices About Enteral Nutrition.
Nutr Clin Pract
April 2020
Orlando VAMC, Orlando, Florida, USA.
Many protocols and steps in the process of enteral nutrition (EN) use are not overly supported with strong research and have been done the same way over many years without questioning the use of best-practices evidence. This article reports many of the myths and unfounded practices surrounding EN and attempts to refute those myths with current evidence. These practices include those about enteral access devices, formulas, enteral administration, and complications.
View Article and Find Full Text PDFThe Development of Oral Amphotericin B to Treat Systemic Fungal and Parasitic Infections: Has the Myth Been Finally Realized?
Pharmaceutics
February 2019
College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 2Z4, Canada.
Parenteral amphotericin B has been considered as first-line therapy in the treatment of systemic fungal and parasitic infections, however its use has been associated with a number of limitations including affordability, accessibility, and an array of systemic toxicities. Until very recently, it has been very challenging to develop a bioavailable formulation of amphotericin B due to its physical chemical properties, limited water and lipid solubility, and poor absorption. This perspective reviews several novel oral Amphotericin B formulations under development that are attempting to overcome these limitations.
View Article and Find Full Text PDFGlutathione for skin lightening: a regnant myth or evidence-based verity?
Dermatol Pract Concept
January 2018
Consultant Dermatologist & Cosmetologist, New Delhi, India.
The recent hype surrounding the antimelanogenic properties of glutathione has resulted in physicians frequently administering it as a "wonder" drug for skin lightening and treatment of hyperpigmentation, especially in ethnic populations with darker skin tones. This phenomenon has seen a recent surge owing to aggressive marketing and capitalization of pharma-cosmeceutical companies. However, the unbridled and prodigal use of it, especially as a parenteral formulation, seems unjustified, given the lacunae in our knowledge about its antimelanogenic potential, limited clinical evidence favoring its role in skin lightening, and the statutory ban/advisory issued by certain federal agencies.
View Article and Find Full Text PDFMyth: parenteral ketorolac provides more effective analgesia than oral ibuprofen.
CJEM
January 2007
Keck School of Medicine, Los Angeles County, University of Southern California, Department of Emergency Medicine, Los Angeles, California 90033, USA.
["Hepatitis" A virus g: myth or reality? VHG/GBH-C: diagnosis, epidemiology, transfusion risk, and pathogenicity].
Rev Med Liege
September 1998
Service d'Immuno-Hématologie et de Transfusion, Université de Liège.
The recently discovered G virus (also called either GBV-C or HGV) is transmitted by blood transfusion as well as by sexual intercourse. The global prevalence of GBV-C is high, not only in those groups classically known to be exposed to parenteral risks (i.v.
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