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Bilateral renal haematuria and obstructive renal failure from acquired haemophilia A: a medical cause for a surgical problem.
BMJ Case Rep
December 2020
Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
A 55-year-old male presented to our emergency department with haematuria and abdominal pain. Investigations including a computed tomography (CT) scan revealed an intraluminal filling defect within the left collecting system, consistent in appearance with blood clot. With an initial working diagnosis of upper tract urothelial cell carcinoma, he was discharged with plans for an urgent cystoscopy and ureteroscopy.
View Article and Find Full Text PDFLife-Threatening Tongue and Retropharyngeal Hemorrhage in a Patient with Hemophilia A with Inhibitors.
Am J Case Rep
July 2019
Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
BACKGROUND Massive tongue hemorrhage in patients with hemophilia is a medical emergency because it can lead to airway obstruction. However, managing bleeding in patients with inhibitors is more difficult than in patients without inhibitors. We report a case of life-threatening massive tongue and retropharyngeal hematoma in a patient with hemophilia A who had inhibitors.
View Article and Find Full Text PDFUse of recombinant activated Factor VII for refractory after lung transplant bleeding as an effective strategy to restrict blood transfusion and associated complications.
Transfusion
April 2013
John McCarthy Intensive Care Unit, the Department of Cardiothoracic Surgery, and the Critical Care Research Group, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Background: Recombinant activated factor VIIa (rFVIIa) has been increasingly used to stop massive bleeding after cardiothoracic surgical procedures. However, the risk : benefit profile of such a potent hemostatic agent remains unclear in the postsurgical patient, and the cost benefit is even less clear. In patients after lung transplantation, volume of blood transfused is of major concern, and all attempts are made to minimize large blood transfusions in this cohort.
View Article and Find Full Text PDFSuccessful use of recombinant factor VIIa in a preterm infant with life-threatening haematuria.
Blood Coagul Fibrinolysis
October 2009
Department of Children's and Adolescent's Medicine, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany.
We report the case of a preterm male infant with a gestational age of 28 + 1 weeks and birth weight of 715 g who presented with life-threatening haematuria on day 28 of life. The haematuria was unresponsive to administration of platelet concentrates and fresh frozen plasma, but then successfully treated with recombinant factor VIIa. The resulting obstructive uropathy was managed by continuous bladder irrigation through suprapubic and urethral catheters.
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