Purpose: To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate.
Design: Observational case report.
Methods: A retrospective case review of a patient with cicatricial ectropion caused by PRP.
Results: A 82-year-old female presented with bilateral lower eyelid cicatricial ectropion secondary to PRP. The patient did not systemically respond to conventional oral retinoid therapy. She was treated with low-dose methotrexate and experienced dramatic resolution of her signs and symptoms, including complete resolution of her bilateral cicatricial ectropion.
Conclusion: Systemic treatment of PRP with low-dose methotrexate may result in successful treatment of cicatricial ectropion without surgery.
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| http://dx.doi.org/10.1016/j.ajo.2006.11.038 | DOI Listing |
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