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Melatonin: A Review of the Evidence for Use in Hospital Settings.
Pharmacol Res Perspect
February 2025
Medication Safety (Formulary) Clinical Excellence Commission, Sydney, New South Wales, Australia.
New onset insomnia is often experienced by patients during hospitalization due to environmental disruptions, pain and increased patient care activities. Patient distress arising from poor sleep quality and quantity often results in the prescribing of hypnotics. Melatonin use in hospital settings is common and is increasingly used for off label indications including primary insomnia in those aged < 55 years, prevention of delirium and to facilitate benzodiazepine discontinuation.
View Article and Find Full Text PDFDelirium is an acute change in attention and awareness that fluctuates and is accompanied by cognitive impairment. Patients with delirium may have disorders of perception such as hallucinations and delusions. The condition is triggered by acute illness or injury, and the risk is highest in sick older patients and patients in intensive care.
View Article and Find Full Text PDFEffects of Sensory-Based Interventions on Delirium Prevention in Critically Ill Patients: A Systematic Review and Meta-Analysis.
Int J Nurs Pract
February 2025
Department of Critical Care Medicine, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Objective: To identify, appraise and synthesize current evidence on different sensory-based interventions on delirium prevention in critically ill patients.
Data Sources: A comprehensive electronic literature search was performed in the PubMed, Embase, Cumulative Index of Nursing and Allied Health Literature, Cochrane Library, China Biology Medicine, China National Knowledge Infrastructure, Wanfang and WeiPu databases from inception to 2 June 2022. The data were updated on 24 December 2022.
Intravenous dexmedetomidine for delirium prevention in elderly patients following orthopedic surgery: a meta-analysis of randomized controlled trials.
BMC Pharmacol Toxicol
January 2025
Department of general medicine, Ordos Central Hospital, Ordos School of Clinical Medicine, Inner Mongolia Medical University, 23 Yijinhuoluo West Street, Dongsheng District, Ordos, Inner Mongolia, 017000, PR China.
Objectives: We conducted a meta-analysis to investigate the effect of dexmedetomidine on postoperative delirium in elderly orthopedic surgery patients.
Methods: A meta-analysis was conducted to identify randomized controlled trials of dexmedetomidine in elderly patients undergoing orthopedic surgery. The data was published on October 25, 2024.
Investigating assumptions in motivational interviewing among general practitioners: a qualitative study.
BMC Prim Care
January 2025
Department of General Practice, University of Western Brittany, 22, Av. Camille Desmoulins, FR 29238, Brest, France.
Background: Unhealthy behaviours contributing to cardiovascular issues, diabetes, strokes, and cancer, pose significant health risks. General practitioners (GPs) are pivotal in guiding behaviour change, with Motivational Interviewing (MI) showing promise. MI, developed by William Miller and Stephen Rollnick, aims to enhance motivation for change.
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