Background: Methylmercury exposure causes a variety of adverse effects on human health. Per capita estimates of mercury exposure are critical for risk assessments and for developing effective risk management strategies.
Objective: This study investigated the impact of natural stochasticity in mercury concentrations among fish and shellfish harvested from the Atlantic Ocean, Pacific Ocean, and foreign shores on estimated mercury exposures.
Methods: Mercury concentrations and seafood consumption are grouped by supply region (Atlantic Ocean, Pacific Ocean, and foreign shores). Distributions of intakes from this study are compared with values obtained using national FDA (Food and Drug Administration) mercury survey data to assess the significance of geographic variability in mercury concentrations on exposure estimates.
Results: Per capita mercury intake rates calculated using FDA mercury data differ significantly from those based on mercury concentration data for each supply area and intakes calculated for the 90th percentile of mercury concentrations.
Conclusions: Differences in reported mercury concentrations can significantly affect per capita mercury intake estimates, pointing to the importance of spatially refined mercury concentration data. This analysis shows that national exposure estimates are most influenced by reported concentrations in imported tuna, swordfish, and shrimp; Pacific pollock; and Atlantic crabs. Collecting additional mercury concentration data for these seafood categories would improve the accuracy of national exposure estimates.
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http://dx.doi.org/10.1289/ehp.9377 | DOI Listing |
Am J Physiol Cell Physiol
January 2025
Laboratoire de Physiopathologie et Régulation des Transports Ioniques, Université de Poitiers, France.
Despite the importance of ocular surface in human physiology and diseases, little is known about ion channel expression, properties and regulation in ocular epithelial cells. Furthermore, human primary epithelial cells have rarely been studied in favor of rat, mouse and especially rabbit animal models. Here, we developed primary human Meibomian gland (hMGEC) and conjunctival (hConEC) epithelial cells.
View Article and Find Full Text PDFAquat Toxicol
January 2025
School of Public Health, Chongqing Medical University, Chongqing, 401331, China. Electronic address:
Nano-plastics (NPs) and heavy metals have attracted growing scientific attention because of both pollutants' wide distribution and ecotoxicity. However, the long-term combined toxicity of NPs and mercury (Hg) on planktonic copepods, a crucial presence in marine environments, is unknown. Here, our study aimed to investigate the multigenerational phenotypic responses of the planktonic copepod Pseudodiaptomus annandalei to polystyrene NPs (about 50 nm) and Hg (alone or combined) at environmentally realistic concentrations (23 μg/L for NPs and 1 μg/L for Hg), and the underlying molecular mechanisms were explored.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Elevated methylmercury (MeHg) exposure poses significant risks to bird health, behavior, and reproduction. Still, the risk of MeHg exposure to forest birds, accounting for over 80 % of the world's bird species, is poorly understood. This study combines Hg isotopes and video analysis, aiming to assess MeHg exposure risks to a forest riverine songbird, the spotted forktail (Enicurus maculatus) from a remote subtropical montane forest.
View Article and Find Full Text PDFHeliyon
January 2025
Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo, P.O. Box 74, New Cairo, 11835, Egypt.
Heavy metals like lead, mercury, cadmium, and arsenic are environmental pollutants that accumulate in ecosystems and pose significant health risks to humans and wildlife, primarily through food chain contamination where plants absorb heavy metals, affecting their growth and threatening consumer health. Cognitive and cardiovascular functions are particularly affected by exposure to heavy metals even at low concentrations through the induction of oxidative stress. Various analytical techniques are used in measuring heavy metals in different environmental and biological samples.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Freshwater product consumption is a major source of mercury (Hg) exposure in China. This study analyzed Hg concentrations in 12,560 samples from 29 provinces across China (2010-2021) and conducted probabilistic health risk assessments across various life stages. The average Hg concentration in China's freshwater products was 40.
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