Objective: Type-D or "distressed" personality and depression following admission for acute coronary syndrome (ACS) have been associated with poor clinical outcome. The biological pathways underpinning this relationship may include disruption of the hypothalamic-pituitary-adrenocortical (HPA) axis. We therefore assessed cortisol output in patients who had recently suffered from ACS.
Method: Salivary cortisol was assessed eight times over a 24-h period in 72 patients within 5 days of admission for ACS. Depressive symptoms were measured with the Beck Depression Inventory (BDI), and type-D personality was measured with the Type-D Scale-16. Particular attention was given to cortisol awakening response (CAR), which was measured as the difference in cortisol between waking and peak responses 15-30 min later.
Results: Cortisol showed a typical diurnal pattern, with low levels in the evening, high levels early in the day, and CAR averaging 7.58+/-10.0 nmol/l. Cortisol was not related to the severity of ACS or underlying coronary artery disease or to BDI scores. The CAR was positively associated with type-D personality independently of age, gender, and body mass (P=.007). Linear regression showed that type-D personality accounted for 7.9% of the variance in CAR after age, sex, body mass, BDI, cortisol level on waking, and fatigue had been taken into account (P=.008).
Conclusions: Type-D personality may be associated with disruption of HPA axis function in survivors of acute cardiac events and may contribute to heightened inflammatory responses influencing future cardiac morbidity.
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http://dx.doi.org/10.1016/j.jpsychores.2006.11.005 | DOI Listing |
Asia Pac J Oncol Nurs
December 2024
Northern Jiangsu People's Hospital, Yangzhou, China.
Objective: To explore the mediating effect of social isolation between perceived social support and type D personality in gastrointestinal cancer survivors based on the WHITE heuristic cognitive-behavioral model of emotion cognition theory.
Methods: The study utilized a convenience sampling method to recruit 183 survivors of gastrointestinal cancer who were undergoing chemoradiotherapy. SPSS 26.
Eur J Prev Cardiol
November 2024
Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Aims: Type D personality has been established as an independent psychological risk factor for adverse outcomes in coronary artery disease (CAD) patients. However, research on the association between Type D personality and cardiovascular events in couples is limited. This study investigated the correlation between Type D personality and cardiovascular outcomes among CAD patients and their spouses.
View Article and Find Full Text PDFJ Psychosom Res
January 2025
CoRPS Center of Research on Psychology in Somatic Diseases, Tilburg University, Tilburg, the Netherlands.
Objective: Type D (Distressed) personality combines negative affectivity (NA) and social inhibition (SI) and is associated with an increased risk of cardiometabolic diseases. Here, we examined the association of Type D traits with 230 (predominantly) lipid metabolites and metabolite ratios.
Methods: Four Dutch cohorts were included, comprising 10,834 individuals.
Psychiatr Danub
May 2024
School of Medicine, University of Zagreb, Zagreb, Croatia.
Psoriasis is a multifactorial, inflammatory, chronic disease caused by the complex interaction of genetic and environmental factors, including psychosocial distress. This review reasons the importance of the biopsychosocial model and why it should be considered when treating patients with psoriasis. We aimed to provide current evidence for the psychological etiopathogenesis, psychosocial comorbidities, psychosocial assessment, and psychological therapeutic interventions in psoriasis.
View Article and Find Full Text PDFWest J Nurs Res
December 2024
School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
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