The authors report on a case of Pott's disease in a patient attending a long-term psychiatric hospital for about 34 years. Difficulties regarding case management concern either diagnosis, due to the numerous and misleading comorbidities, or pharmacological treatment, due to both the interference between neurotropic and antitubercular drugs and the capacity of some antimycobacterial drugs to reduce significantly the epileptogenic threshold, thus enhancing epileptic crises.
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