AI Article Synopsis
- Placental mesenchymal dysplasia is a rare condition characterized by an enlarged placenta with abnormal structures that can resemble a partial hydatidiform mole but can occur alongside a healthy fetus.
- In a case study, this disorder led to preterm labor at 33 weeks, fetal distress, and complications including a large hepatic cyst that required surgical intervention.
- Despite intensive medical care, the newborn suffered from severe health issues and ultimately died, with findings confirming a link between placental mesenchymal dysplasia and a liver tumor known as a mesenchymal hamartoma.
Article Abstract
Placental mesenchymal dysplasia is an uncommon disorder in which the placenta is enlarged with abnormal, large, and often cystic villi with dilated and/or thick-walled vessels. These placental changes can mimic a partial hydatidiform mole but in contrast to a partial mole can coexist with a fully viable fetus. Fetal anatomical and vascular anomalies frequently coexist with placental mesenchymal dysplasia. In this case, placental mesenchymal dysplasia was associated with preterm labor at 33 weeks' gestation, fetal compromise, and a large abdominal mass with a large hepatic cyst that was de-roofed at exploratory laparotomy. The neonate remained critically ill with hypoxic ischaemic encephalopathy and coagulopathy and died despite intensive care. Biopsy and autopsy findings showed a large cystic mesenchymal hamartoma affecting the left lobe of the liver. This appears to be the 3rd histologically confirmed association of placental mesenchymal dysplasia with mesenchymal hamartoma of the liver in the English language literature.
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| http://dx.doi.org/10.2350/06-03-0066.1 | DOI Listing |
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