Good for Goose, but not for Gander: IL-2 interferes with Th17 differentiation.

Immunity

Division of Molecular Immunology, The MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

Published: March 2007

In this issue of Immunity, Laurence et al. (2007) examined the effects of interleukin-2 on differentiation of the T helper 17 (Th17) cells and found that this essential growth factor for all other T cell subsets blocks the development of Th17 T cells.

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http://dx.doi.org/10.1016/j.immuni.2007.03.001DOI Listing

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