Reaction of 1-(2-chloro-5-nitrophenyl)ethanone 1, via Willgerodt-Kindler routes, using the primary and secondary amines 2a-k resulted in a simple, efficient three-component one-pot synthesis of 2-aminobenzo[b]thiophenes 3a-k.
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| http://dx.doi.org/10.1021/jo062141a | DOI Listing |
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