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Letter to editor: comment on, "Imaging manifestations of papillary glioneuronal tumors".

Neurosurg Rev

September 2024

Department of Cariology, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Dental College and Hospitals, Saveetha University, Chennai, 600 077, India.

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Brain arteriovenous malformations (AVM) rarely occur with spatial and/or temporal co-localisation to intracranial neoplasms. Most prior reports describe this association with high-grade gliomas; however, reports of a co-occurrence with low grade gliomas are very rare. It is unclear whether such cases represent a true co-occurrence of separate pathologies or simply an unusually vascular phenotype of the neoplasm.

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Papillary glioneuronal tumors (PGNTs), classified as Grade I by the WHO in 2016, present diagnostic challenges due to their rarity and potential for malignancy. Xiaodan Du et al.'s recent study of 36 confirmed PGNT cases provides critical insights into their imaging characteristics, revealing frequent presentation with headaches, seizures, and mass effect symptoms, predominantly located in the supratentorial region near the lateral ventricles.

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Article Synopsis
  • Low-grade gliomas are the most common brain tumors in children and adolescents, often leading to uncontrolled seizures when located in the temporal lobe.
  • A review of literature highlights various tumor types, surgical treatment options, and outcomes, indicating that complete resection of tumors is crucial for achieving favorable seizure outcomes.
  • Management of these conditions should involve a multidisciplinary team focused on epilepsy surgery, as early and effective intervention significantly improves patient survival and reduces seizure-related issues.
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