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Scleredema: An Unusual Cutaneous Manifestation of Coronavirus Infection.
Adv Skin Wound Care
January 2025
In the Department of Dermatology, Employees' State Insurance Corporation-Post Graduate Institute of Medical Sciences and Research, in Basaidarapur, New Delhi, India. Priyanka Hemrajani, MD, is Assistant Professor; Mona Sharma, MD, and Piyush Gupta, MD, are Senior Residents; Tapan Kumar Dhali, MD, is Professor; and Paschal D'souza, MD, is Professor and Head of Department. The authors have disclosed no financial relationships related to this article. Submitted April 8, 2023; accepted in revised form April 2, 2024.
The global pandemic caused by COVID-19 led to numerous novel cases of autoimmune and rheumatologic disorders that developed postinfection. Along these lines, these authors report an unusual case of scleredema following SARS-CoV-2 infection in an individual who lacked any known risk factors. Given the emergence of newer mutant strains of COVID-19 and steadily rising numbers of people receiving COVID-19 vaccinations, physicians should remain alert for as yet unrecognized manifestations of the disease.
View Article and Find Full Text PDFSCLEREDEMA DIABETICORUM; A RARE DISEASE.
J Ayub Med Coll Abbottabad
November 2024
Pakistan Institute of Medical Sciences, Islamabad-Pakistan.
Scleredema Diabeticorum (SD) is a rare condition characterized by diffuse, symmetrical induration along with non-pitted swelling mostly on the upper back as a result of mucin being deposited in the dermis. It can also involve posterior neck, shoulders, and scalp. We report a case of 48 years old female patient from Pakistan, with uncontrolled diabetes mellites type 2 for the last 15 years, presenting with thickened skin at the back of the neck resulting in difficulty in neck and shoulder movements.
View Article and Find Full Text PDFDiabetes-Associated Scleredema.
N Engl J Med
August 2024
Lewisham and Greenwich NHS Trust, London, United Kingdom
Macroglossia and lip edema: A case of paraproteinemia-associated scleredema responsive to intravenous immunoglobulins.
JAAD Case Rep
February 2024
Division of Dermatology, Montefiore Einstein, Albert Einstein College of Medicine, Bronx, New York.
Treatment of scleredema adultorum of Buschke with intravenous immunoglobulin and mycophenolate mofetil in a 14-year-old girl: a case report.
J Med Case Rep
February 2024
Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Article Synopsis
- * A case is presented involving a 14-year-old girl from Iran who experienced rapid progression of skin thickening, ruled out for malignancies and connective tissue disorders before being diagnosed with scleredema.
- * The report emphasizes the potential effectiveness of intravenous immunoglobulin and mycophenolate mofetil in treating this rare disease, despite the lack of definitive treatments available.
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