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Towards a Greener Future: Sustainable Innovations in the Extraction of Lavender ( spp.) Essential Oil.
Foods
January 2025
Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz 7134845794, Iran.
Lavender is one of the most appreciated aromatic plants, with high economic value in food, cosmetics, perfumery, and pharmaceutical industries. Lavender essential oil (LEO) is known to have demonstrative antimicrobial, antioxidant, therapeutic, flavor and fragrance properties. Conventional extraction methods, e.
View Article and Find Full Text PDFComputer-Aided Retrosynthesis for Greener and Optimal Total Synthesis of a Helicase-Primase Inhibitor Active Pharmaceutical Ingredient.
JACS Au
November 2024
Department of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.
This study leverages and upgrades the capabilities of computer-aided retrosynthesis (CAR) in the systematic development of greener and more efficient total synthetic routes for the active pharmaceutical ingredient (API) IM-204, a helicase-primase inhibitor that demonstrated enhanced efficacy against Herpes simplex virus (HSV) infections. Using various CAR tools, several total synthetic routes were uncovered, evaluated, and experimentally validated, with the goal to maximize selectivity and yield and minimize the environmental impact. The CAR tools revealed several synthetic options under different constraints, which can overperform the patented synthetic route used as a reference.
View Article and Find Full Text PDFEnhancing road performance and sustainability: A study on recycled porous warm mix asphalt.
Sci Total Environ
January 2025
Department of Civil, Chemical, Environmental and Materials Engineering, University of Bologna, Via U. Terracini 28, 40131 Bologna, BO, Italy.
The growing demand for sustainable infrastructure has increased interest in eco-friendly design solutions such as porous asphalt (PA) pavements, which manage stormwater runoff and mitigate urban heat islands, and warm mix asphalt (WMA), which reduces energy consumption and emissions during production. This study evaluates the mechanical and environmental performance of four warm mix porous asphalt (WPA) mixtures incorporating recycled materials and by-products: reclaimed asphalt pavement (RAP), aramid pulp fibres, and electric arc furnace (EAF) steel slag. A Life Cycle Assessment (LCA) with a cradle-to-cradle approach was conducted to comprehensively assess environmental impacts.
View Article and Find Full Text PDFSilanization of Starch and Its Effect on Cross-Linking and Mechanical, Dynamic, Hydrophobic, and Aging Properties of Polymeric Compositions Containing Natural Rubber.
Materials (Basel)
December 2024
Institute of Polymer and Dye Technology, Faculty of Chemistry, Lodz University of Technology, Stefanowskiego Street 16, 90-537 Lodz, Poland.
In recent years, the search for more sustainable fillers for elastomeric composites than silica and carbon black has been underway. In this work, silanized starch was used as an innovative filler for elastomeric composites. Corn starch was chemically modified by silanization (with n-octadecyltrimethoxysilane) via a condensation reaction to produce a hydrophobic starch.
View Article and Find Full Text PDFA Biorefinery Approach Integrating Lipid and EPS Augmentation Along with Cr (III) Mitigation by .
Cells
December 2024
Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee 247667, India.
The quest for cleaner and sustainable energy sources is crucial, considering the current scenario of a steep rise in energy consumption and the fuel crisis, exacerbated by diminishing fossil fuel reserves and rising pollutants. In particular, the bioaccumulation of hazardous substances like trivalent chromium has not only disrupted the fragile equilibrium of the ecological system but also poses significant health hazards to humans. Microalgae emerged as a promising solution for achieving sustainability due to their ability to remediate contaminants and produce greener alternatives such as biofuels.
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