The purpose of this study was to assess the validity of the FitMate metabolic system (Cosmed, Rome, Italy) in measuring oxygen consumption during graded exercise. The FitMate is a new, small (20 x 24 cm) metabolic analyzer designed for measurement of oxygen consumption during rest and exercise. Subjects included 40 healthy adults (N = 20 males, N = 20 females) ranging in age from 18 to 37 kg/m2 (mean +/- SD age, 22.5 +/- 3.6 years) and body mass index (BMI) from 18.3 to 32.5 kg/m2 (23.2 +/- 3.3 years). One-minute FitMate and Douglas bag measurements were made during steady state conditions at the end of each 3-minute stage of the Bruce treadmill graded exercise test, and subjects continued until they could not attain steady state exercise during a stage. Oxygen consumption difference scores (Douglas bag minus FitMate measurements) did not differ between males and females, so data were combined and analyzed for the entire group. During the first three stages, mean oxygen consumption did not differ significantly between the Douglas bag and FitMate systems (26.5 +/- 1.1 and 26.7 +/- 1.3 ml.kg-1.min-1, respectively, P = 0.140) with a mean absolute difference of 0.23 +/- 0.91 ml.kg-1.min-1 or 14.2 +/- 67.5 ml.min-1. In conclusion, the FitMate metabolic system accurately measures oxygen consumption during graded treadmill exercise when compared with the Douglas bag system in male and female adults.
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http://dx.doi.org/10.1080/15438620601184380 | DOI Listing |
Sports Med Health Sci
March 2025
Laboratory of Exercise Biochemistry, University of Taipei, Taipei City, Taiwan, China.
Constipation is correlated with diminished cognitive function, revealing a possible rectum-brain connection. In this counter-balanced crossover trial, 13 elite triathletes underwent a Stroop test to assess cognitive function and executive control. The Stroop test was conducted both with and without magnesium oxide intake, with a 1-week washout period between sessions.
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Kresge Eye Institute, Wayne State University, Detroit, MI, USA.
Diabetic retinopathy, a microvascular complication of diabetes, is the leading cause of blindness in adults, but the molecular mechanism of its development remains unclear. Retinal mitochondrial DNA is damaged and hypermethylated, and mtDNA-encoded genes are downregulated. Expression of a long noncoding RNA (larger than 200 nucleotides, which does not translate into proteins), encoded by mtDNA, cytochrome B (Lnc), is also downregulated.
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Diabetes and Endocrinology, United Lincolnshire Hospital NHS Trust, Lincoln, GBR.
The cardiovascular implications of thyroid disease have been recognized as one of the most characteristic signs that result from the effect of thyroid hormone (TH). Both hyperthyroidism and hypothyroidism produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood pressure, and systemic vascular resistance. The bradyarrhythmias, including atrioventricular block and sick sinus syndrome, are exceedingly rare in hyperthyroidism.
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January 2025
Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
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